Does the autonomic nervous system contribute to the initiation and progression of prostate cancer

In the July 12 issue of Science maga-zine, researchers from the AlbertEinstein College of Medicine, the Mount Sinai School of Medicine, the Durham VA Medical Centre and Duke University published an elegant study demonstrating that the sym-pathetic nervous system, acting through β2 and β3-adrenocepto...

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Bibliographic Details
Published in:Asian journal of andrology 2013-11, Vol.15 (6), p.715-716
Main Authors: Ventura, Sabatino, Evans, Bronwyn A
Format: Article
Language:English
Subjects:
Adenocarcinoma - pathology
Animals
Autonomic Nervous System - growth & development
Humans
Male
Neurogenesis
Prostate - innervation
Prostate - pathology
Prostatic Neoplasms - pathology
Research Highlight
交感神经系统
前列腺癌
医学院
植物
研究人员
肾上腺素能受体
肿瘤转移
自主神经系统
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Summary:In the July 12 issue of Science maga-zine, researchers from the AlbertEinstein College of Medicine, the Mount Sinai School of Medicine, the Durham VA Medical Centre and Duke University published an elegant study demonstrating that the sym-pathetic nervous system, acting through β2 and β3-adrenoceptors in the prostate, plays an important role in the initiation of prostate can-cer, while the parasympathetic nervous system plays a role in the dissemination of tumour metastases via M1 muscarirdc receptors. These findings are significant because they indicate that receptors associated with the autonomic nervous system may be viable tar-gets for prostate cancer therapy.
ISSN:1008-682X
1745-7262
DOI:10.1038/aja.2013.114