A Voxel-Map Quantitative Analysis Approach for Atherosclerotic Noncalcified Plaques of the Coronary Artery Tree

Noncalcified plaques (NCPs) are associated with the presence of lipid-core plaques that are prone to rupture. Thus, it is important to detect and monitor the development of NCPs. Contrast-enhanced coronary Computed Tomography Angiography (CTA) is a potential imaging technique to identify atheroscler...

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Bibliographic Details
Published in:Computational and mathematical methods in medicine 2013-01, Vol.2013 (2013), p.1-9
Main Authors: Li, Ying, Chen, Wei, Liu, Kaijun, Wu, Yi, Chen, Yonglin, Chu, Chun, Fang, Bingji, Tan, Liwen, Zhang, Shao-Xiang
Format: Article
Language:English
Subjects:
Algorithms
Contrast Media
Coronary Angiography
Coronary Vessels - physiopathology
Humans
Image Processing, Computer-Assisted
Imaging, Three-Dimensional
Models, Anatomic
Models, Theoretical
Percutaneous Coronary Intervention
Plaque, Atherosclerotic - physiopathology
Radiographic Image Interpretation, Computer-Assisted
Software
Tomography, X-Ray Computed
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Summary:Noncalcified plaques (NCPs) are associated with the presence of lipid-core plaques that are prone to rupture. Thus, it is important to detect and monitor the development of NCPs. Contrast-enhanced coronary Computed Tomography Angiography (CTA) is a potential imaging technique to identify atherosclerotic plaques in the whole coronary tree, but it fails to provide information about vessel walls. In order to overcome the limitations of coronary CTA and provide more meaningful quantitative information for percutaneous coronary intervention (PCI), we proposed a Voxel-Map based on mathematical morphology to quantitatively analyze the noncalcified plaques on a three-dimensional coronary artery wall model (3D-CAWM). This approach is a combination of Voxel-Map analysis techniques, plaque locating, and anatomical location related labeling, which show more detailed and comprehensive coronary tree wall visualization.
ISSN:1748-670X
1748-6718
DOI:10.1155/2013/957195