The impact of saddle embolism on the major adverse event rate of patients with non-high-risk pulmonary embolism

Wider application of CT angiography (CTA) improves the diagnosis of acute pulmonary embolism (PE). It also permits the visualisation of saddle embolism (SE), namely thrombi, which are located at the bifurcation of the main pulmonary artery. The aim of this study was to assess the prevalence of SE an...

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Published in:British journal of radiology 2013-12, Vol.86 (1032), p.20130273
Main Authors: Kwak, M K, Kim, W Y, Lee, C W, Seo, D W, Sohn, C H, Ahn, S, Lim, K S, Donnino, M W
Format: Article
Language:English
Subjects:
Aged
Angiography - methods
Female
Humans
Male
Middle Aged
Prognosis
Pulmonary Artery - diagnostic imaging
Pulmonary Embolism - complications
Pulmonary Embolism - diagnostic imaging
Pulmonary Embolism - mortality
Retrospective Studies
Risk Assessment
Risk Factors
Survival Rate
Tomography, X-Ray Computed - methods
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cited_by cdi_FETCH-LOGICAL-c384t-898ea26956750db9759931db6d9c7d9f850f3a1188a0971a500fa1dd784efca03
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container_issue 1032
container_start_page 20130273
container_title British journal of radiology
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creator Kwak, M K
Kim, W Y
Lee, C W
Seo, D W
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Ahn, S
Lim, K S
Donnino, M W
description Wider application of CT angiography (CTA) improves the diagnosis of acute pulmonary embolism (PE). It also permits the visualisation of saddle embolism (SE), namely thrombi, which are located at the bifurcation of the main pulmonary artery. The aim of this study was to assess the prevalence of SE and whether SE predicts a complicated clinical course in patients with non-high-risk PE. In total, 297 consecutive patients with non-high-risk PE confirmed using CTA in the emergency department were studied. The presence of SE and its ability to predict the occurrence of major adverse events (MAEs) within 1 month were determined. Of the 297 patients, 27 (9.1%) had an SE. The overall mortality at 1 month was 12.5%; no significant difference was observed between the SE and non-SE groups (18.5% vs 11.9%, p=0.32). However, patients with SE were more likely to receive thrombolytic therapy (29.6% vs 8.1%, p
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It also permits the visualisation of saddle embolism (SE), namely thrombi, which are located at the bifurcation of the main pulmonary artery. The aim of this study was to assess the prevalence of SE and whether SE predicts a complicated clinical course in patients with non-high-risk PE. In total, 297 consecutive patients with non-high-risk PE confirmed using CTA in the emergency department were studied. The presence of SE and its ability to predict the occurrence of major adverse events (MAEs) within 1 month were determined. Of the 297 patients, 27 (9.1%) had an SE. The overall mortality at 1 month was 12.5%; no significant difference was observed between the SE and non-SE groups (18.5% vs 11.9%, p=0.32). However, patients with SE were more likely to receive thrombolytic therapy (29.6% vs 8.1%, p&lt;0.01) and had significantly more MAEs (59.3% vs 25.6%, p&lt;0.01). At the time of diagnosis, SE, as determined using CTA, is associated with the development of MAE within 1 month. 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source Oxford Journals Online; Alma/SFX Local Collection
subjects Aged
Angiography - methods
Female
Humans
Male
Middle Aged
Prognosis
Pulmonary Artery - diagnostic imaging
Pulmonary Embolism - complications
Pulmonary Embolism - diagnostic imaging
Pulmonary Embolism - mortality
Retrospective Studies
Risk Assessment
Risk Factors
Survival Rate
Tomography, X-Ray Computed - methods
title The impact of saddle embolism on the major adverse event rate of patients with non-high-risk pulmonary embolism
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