Cannabis use and involuntary admission may mediate long-term adherence in first-episode psychosis patients: a prospective longitudinal study

This study aimed to examine factors associated with treatment adherence in first-episode psychosis (FEP) patients followed up over 8 years, especially involuntary first admission and stopping cannabis use. This prospective, longitudinal study of FEP patients collected data on symptoms, adherence, fu...

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Bibliographic Details
Published in:BMC psychiatry 2013-12, Vol.13 (1), p.326-326, Article 326
Main Authors: Barbeito, Sara, Vega, Patricia, Ruiz de Azúa, Sonia, Saenz, Margarita, Martinez-Cengotitabengoa, Mónica, González-Ortega, Itxaso, Bermudez, Cristina, Hernanz, Margarita, Corres, Blanca Fernández de, González-Pinto, Ana
Format: Article
Language:English
Subjects:
Adolescent
Adult
Antipsychotic Agents - therapeutic use
Biomedical research
Care and treatment
Distance learning
Drug use
Female
Health aspects
Hospitalization
Hospitals
Humans
Longitudinal Studies
Male
Marijuana
Marijuana Smoking - psychology
Medication Adherence - psychology
Mental disorders
Middle Aged
Patient compliance
Prospective Studies
Psychiatry
Psychopathology
Psychoses
Psychosis
Psychotic Disorders - diagnosis
Psychotic Disorders - drug therapy
Psychotic Disorders - psychology
Risk factors
Schizophrenia
Studies
Substance abuse
Suicides & suicide attempts
Variables
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Summary:This study aimed to examine factors associated with treatment adherence in first-episode psychosis (FEP) patients followed up over 8 years, especially involuntary first admission and stopping cannabis use. This prospective, longitudinal study of FEP patients collected data on symptoms, adherence, functioning, and substance use. Adherence to treatment was the main outcome variable and was categorized as 'good' or 'bad'. Cannabis use during follow-up was stratified as continued use, stopped use, and never used. Bivariate and logistic regression models identified factors significantly associated with adherence and changes in adherence over the 8-year follow-up period. Of the 98 FEP patients analyzed at baseline, 57.1% had involuntary first admission, 74.4% bad adherence, and 52% cannabis use. Good adherence at baseline was associated with Global Assessment of Functioning score (p = 0.019), Hamilton Depression Rating Scale score (p = 0.017) and voluntary admission (p 
ISSN:1471-244X
1471-244X
DOI:10.1186/1471-244X-13-326