A meta-analysis of the relationship between antidepressant use in pregnancy and the risk of preterm birth and low birth weight

Abstract Objectives To examine the relationship between antidepressant use in pregnancy and low birth weight (LBW) and preterm birth (PTB). Data Sources and Study Selection We searched English and non-English language articles via PubMed, CINAHL and PsychINFO (from their start dates through December...

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Bibliographic Details
Published in:General hospital psychiatry 2014-01, Vol.36 (1), p.13-18
Main Authors: Huang, Hsiang, M.D., M.P.H, Coleman, Shane, M.D., M.P.H, Bridge, Jeffrey A., Ph.D, Yonkers, Kimberly, M.D, Katon, Wayne, M.D
Format: Article
Language:English
Subjects:
Adverse birth outcomes
Antenatal
Antidepressants
Antidepressive Agents - therapeutic use
Biological and medical sciences
Depressive Disorder - drug therapy
Diseases of mother, fetus and pregnancy
Female
Gynecology. Andrology. Obstetrics
Humans
Infant, Low Birth Weight
Infant, Newborn
Low birth weight
Medical sciences
Neuropharmacology
Pharmacology. Drug treatments
Pregnancy
Pregnancy Complications - drug therapy
Pregnancy Outcome
Pregnancy. Fetus. Placenta
Premature Birth
Prenatal
Preterm birth
Psychiatry
Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer
Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease)
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Psychopharmacology
Treatment Outcome
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Summary:Abstract Objectives To examine the relationship between antidepressant use in pregnancy and low birth weight (LBW) and preterm birth (PTB). Data Sources and Study Selection We searched English and non-English language articles via PubMed, CINAHL and PsychINFO (from their start dates through December 1st, 2012). We used the following keywords and their combinations: antidepressant , selective serotonin reuptake inhibitor (SSRI) , pregnancy , antenatal , prenatal , birthweight , birth weight , preterm , prematurity , gestational age , fetal growth restriction , intrauterine growth restriction , and small-for-gestational age . Published studies were considered eligible if they examined exposure to antidepressant medication use during pregnancy and reported data on at least one birth outcome of interest: PTB (
ISSN:0163-8343
1873-7714
DOI:10.1016/j.genhosppsych.2013.08.002