Epithelial adhesive junctions

Epithelial adhesive cell-to-cell contacts contain large, plasma membrane-spanning multiprotein aggregates that perform vital structural and signaling functions. Three prominent adhesive contacts are the tight junction, adherens junction, and the desmosome. Each junction type has unique cellular func...

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Bibliographic Details
Published in:F1000 prime reports 2014-01, Vol.6, p.1-1
Main Authors: Capaldo, Christopher T, Farkas, Attila E, Nusrat, Asma
Format: Article
Language:English
Subjects:
Review
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Description
Summary:Epithelial adhesive cell-to-cell contacts contain large, plasma membrane-spanning multiprotein aggregates that perform vital structural and signaling functions. Three prominent adhesive contacts are the tight junction, adherens junction, and the desmosome. Each junction type has unique cellular functions and a complex molecular composition. In this review, we comment on recent and exciting advances in our understanding of junction composition and function.
ISSN:2051-7599
2051-7599
DOI:10.12703/P6-1