ABO mismatched platelet transfusions in trauma patients

In the study by Nascimento and col- leagues,1 the patients who received increased plasma and platelet transfu- sio n s h a d gr e ater m o rtality d u e to bleeding (22%) than the control group (9%), albeit not statistically signifi- cantly so. Nonetheless, it raises the question of whether the plas...

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Bibliographic Details
Published in:Canadian Medical Association journal (CMAJ) 2014-01, Vol.186 (1), p.63-63
Main Author: Blumberg, Neil
Format: Article
Language:English
Subjects:
Blood Transfusion - methods
Female
Humans
Letters
Male
Wounds and Injuries - therapy
Citations: Items that cite this one
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Summary:In the study by Nascimento and col- leagues,1 the patients who received increased plasma and platelet transfu- sio n s h a d gr e ater m o rtality d u e to bleeding (22%) than the control group (9%), albeit not statistically signifi- cantly so. Nonetheless, it raises the question of whether the plasma and platelet transfusion worsened hemor- rhage rather than mitigated it. One pos- sible mechanism is the administration of A B O n on -i den ti c a l p la s m a an d platelets.
ISSN:0820-3946
1488-2329
DOI:10.1503/cmaj.114-0001