A disseminated infection with the antifungal-multiresistant teleomorphic fungus Neocosmospora vasinfecta in a patient with acute B-lymphoblastic leukemia

We report on a fatal invasive infection due to the ascomycetous fungus Neocosmospora vasinfecta, in a 20-year-old European patient suffering from an acute lymphoblastic leukemia. The infection could not be controlled by a bitherapy combining liposomal amphotericin B and voriconazole. This is the sec...

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Bibliographic Details
Published in:Medical mycology (Oxford) 2013-02, Vol.2, p.44-47
Main Authors: Gabriel, Frédéric, D'Almeida, Mahussi, Albert, Olivier, Fitton-Ouhabi, Valérie, Noël, Thierry, Accoceberry, Isabelle
Format: Article
Language:English
Subjects:
Life Sciences
Microbiology and Parasitology
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Summary:We report on a fatal invasive infection due to the ascomycetous fungus Neocosmospora vasinfecta, in a 20-year-old European patient suffering from an acute lymphoblastic leukemia. The infection could not be controlled by a bitherapy combining liposomal amphotericin B and voriconazole. This is the second case of disseminated infection reported with this unusual fungus, which develops under its teleomorphic state, is fully resistant to all systemic antifungals, and which is known to live in tropical countries.
ISSN:2211-7539
1369-3786
2211-7539
1365-280X
DOI:10.1016/j.mmcr.2013.01.004