The evolution of personalized cancer genetic counseling in the era of personalized medicine

Practice changes in cancer genetic counseling have occurred to meet the demand for cancer genetic services. As cancer genetics continues to impact not only prevention strategies but also treatment decisions, current cancer genetic counseling models will need to be tailored to accommodate emerging cl...

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Bibliographic Details
Published in:Familial cancer 2012-09, Vol.11 (3), p.539-544
Main Authors: Vig, Hetal S., Wang, Catharine
Format: Article
Language:English
Subjects:
Biomedical and Life Sciences
Biomedicine
Breast Neoplasms - genetics
Breast Neoplasms - prevention & control
Breast Neoplasms - surgery
Cancer Research
Colorectal Neoplasms, Hereditary Nonpolyposis - diagnosis
Colorectal Neoplasms, Hereditary Nonpolyposis - genetics
Epidemiology
Female
Genetic Counseling - trends
Heterozygote
Human Genetics
Humans
Letter to the Editor
Microsatellite Instability
Precision Medicine
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Summary:Practice changes in cancer genetic counseling have occurred to meet the demand for cancer genetic services. As cancer genetics continues to impact not only prevention strategies but also treatment decisions, current cancer genetic counseling models will need to be tailored to accommodate emerging clinical indications. These clinical indications include: surgical prophylactic bilateral mastectomy candidates, PARP-inhibitor candidates, patients with abnormal tumor screening results for Lynch syndrome, and post-test counseling patients (after genetic testing is ordered by another healthcare provider). A more personalized, multidisciplinary approach to selecting the best framework, for a given clinical indication, may become increasingly necessary in this era of personalized medicine.
ISSN:1389-9600
1573-7292
DOI:10.1007/s10689-012-9524-8