Kinetics of Thymidine Incorporation into Detergent-Soluble DNA of Mouse Lymphocytes

We reported recently that splenocytes from concanavalin A-stimulated mice rapidly incorporated [3H]thymidine into non-mitochondrial DNA that was detergent soluble and distributed in size classes between 200 and 5000 base pairs. In this report we show that small [3H]thymidine-labeled oligonucleotides...

Full description

Saved in:
Bibliographic Details
Published in:Proceedings of the National Academy of Sciences - PNAS 1984-11, Vol.81 (22), p.7056-7060
Main Authors: Strauss, Phyllis R., Banerjee, Papiya T., LaGree, Karen, Mui, Suet C.
Format: Article
Language:English
Subjects:
Animals
Aphidicolin
Biochemistry
Detergents
Diterpenes - pharmacology
DNA
DNA - biosynthesis
DNA Replication - drug effects
Electrophoresis
Gels
Hydroxyurea - pharmacology
Lymphocyte Activation
Lymphocytes
Lymphocytes - metabolism
Mice
Molecular Weight
Oligonucleotides
Polynucleotides
Solubility
Spleen cells
Splenocytes
Thymidine - metabolism
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We reported recently that splenocytes from concanavalin A-stimulated mice rapidly incorporated [3H]thymidine into non-mitochondrial DNA that was detergent soluble and distributed in size classes between 200 and 5000 base pairs. In this report we show that small [3H]thymidine-labeled oligonucleotides (
ISSN:0027-8424
1091-6490
DOI:10.1073/pnas.81.22.7056