The effect of opium addiction on thyroid function tests

Background A number of abnormalities has been identified among drug addicted users especially heroin addicts. However, there are a few studies to assess the opium effects on thyroid hormones. the aim of the present study is to investigate the effect of opium on the thyroid function tests. Method In...

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Bibliographic Details
Published in:Journal of diabetes and metabolic disorders 2014-01, Vol.13 (1), p.5-5, Article 5
Main Authors: Gozashti, Mohammad Hossein, Mohammadzadeh, Elham, Divsalar, Kouros, Shokoohi, Mostafa
Format: Article
Language:English
Subjects:
Diabetes
Endocrinology
Medicine
Medicine & Public Health
Metabolic Diseases
Research Article
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Summary:Background A number of abnormalities has been identified among drug addicted users especially heroin addicts. However, there are a few studies to assess the opium effects on thyroid hormones. the aim of the present study is to investigate the effect of opium on the thyroid function tests. Method In this case–control, 50 male addicts, aged 20–50 years, with history of addiction to opium lasting more than two years, and 50 male non-addicts as control group were randomly selected. 10 cc blood sample was taken for measurements of TSH, total T4 and T3, free T4 and T3, and T3 resin uptake (T3RU) and 50 cc urine sample for opium testing. Results The univariate analysis revealed that there was not a significant association between opium and serum levels of T4 and TSH, but compared with control group, a slight increase in total T3 and a decrease in T3RU were observed among addicts (P 
ISSN:2251-6581
2251-6581
DOI:10.1186/2251-6581-13-5