Toll-like receptors 2 and 4 modulate autonomic control of heart rate and energy metabolism

Highlight • TLR2 and TLR4 signaling influence autonomic regulation of heart rate (HR) body temperature and energy metabolism in mice.

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Bibliographic Details
Published in:Brain, behavior, and immunity behavior, and immunity, 2014-02, Vol.36, p.90-100
Main Authors: Okun, Eitan, Griffioen, Kathleen J, Rothman, Sarah, Wan, Ruiqian, Cong, Wei-Na, De Cabo, Rafael, Martin-Montalvo, Alejandro, Levette, Andrew, Maudsley, Stuart, Martin, Bronwen, Arumugam, Thiruma Valavan, Mattson, Mark P
Format: Article
Language:English
Subjects:
Allergy and Immunology
Animals
ANS
Autonomic nervous system
Autonomic Nervous System - physiology
Body Temperature
Body Temperature Regulation - physiology
Energy Metabolism - physiology
Heart rate
Heart Rate - physiology
Innate immunity
Male
Mice
Mice, Knockout
Psychiatry
Restraint, Physical
Stress
Stress, Psychological - metabolism
TLR2
TLR4
Toll-Like Receptor 2 - genetics
Toll-Like Receptor 4 - genetics
Toll-like receptors
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Description
Summary:Highlight • TLR2 and TLR4 signaling influence autonomic regulation of heart rate (HR) body temperature and energy metabolism in mice.
ISSN:0889-1591
1090-2139
DOI:10.1016/j.bbi.2013.10.013