Risk factors for therapeutic ERCP-related complications: an analysis of 2,715 cases performed by a single endoscopist

Endoscopic retrograde cholangiopancreatography (ERCP) is now the exclusive endoscopic therapeutic modality for biliary as well as pancreatic diseases. The aim of the present study was to investigate patient- and procedure-related risk factors for post-ERCP complications in a large-scale study of pro...

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Published in:Annals of gastroenterology 2014, Vol.27 (1), p.65-72
Main Authors: Katsinelos, Panagiotis, Lazaraki, Georgia, Chatzimavroudis, Grigoris, Gkagkalis, Stergios, Vasiliadis, Ioannis, Papaeuthimiou, Apostolos, Terzoudis, Sotiris, Pilpilidis, Ioannis, Zavos, Christos, Kountouras, Jannis
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Language:English
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Summary:Endoscopic retrograde cholangiopancreatography (ERCP) is now the exclusive endoscopic therapeutic modality for biliary as well as pancreatic diseases. The aim of the present study was to investigate patient- and procedure-related risk factors for post-ERCP complications in a large-scale study of procedures performed by a single experienced endoscopist. This is a retrospective cohort study which included a total of 2,715 therapeutic ERCPs enrolled in the final analysis. Potential important patient- and procedure-related risk factors for overall post-ERCP complications, pancreatitis and post-endoscopic sphincterotomy (ES) bleeding were investigated by univariate and multivariate analyses. Following the first therapeutic ERCP, 327 patients suffered complications; pancreatitis was observed in 132 (4.9%) patients, hemorrhage in 122 (4.5%) patients, cholangitis in 63 (2.3%) patients, perforation in 3 (0.11%) patients, and basket impaction in 7 (0.26%) patients. History of acute pancreatitis was more common in patients with post-ERCP complications (P
ISSN:1108-7471
1792-7463