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CARDIOLOGY In Women With Coronary Artery Disease, Newer Generation Drug-Eluting Stents Associated With Reduced Risks of Myocardial Infarction and Target Vessel Revascularization Compared to Bare Metal and Early Generation Drug-Eluting Stents A Cochrane review has demonstrated that compared to bare m...

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Bibliographic Details
Published in:The Ochsner journal 2014, Vol.14 (1), p.3-6
Main Author: Ray, Indranill Basu
Format: Article
Language:English
Subjects:
Asthma
Cardiology
Cardiovascular disease
Chronic illnesses
Clinical outcomes
Coronary vessels
Diabetes
Emergency medical care
Health risk assessment
Heart attacks
Heart failure
Medical imaging
Mortality
Patients
Pediatrics
Stents
Systematic review
Testosterone
Womens health
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Summary:CARDIOLOGY In Women With Coronary Artery Disease, Newer Generation Drug-Eluting Stents Associated With Reduced Risks of Myocardial Infarction and Target Vessel Revascularization Compared to Bare Metal and Early Generation Drug-Eluting Stents A Cochrane review has demonstrated that compared to bare metal stents, drug-eluting stents reduce the risk of target lesion revascularization [Cochrane Database Syst Rev 2010 May 12;(5):CD004587], but the large majority of patients with coronary artery disease recruited for clinical studies are male, and these trials may not have been adequately powered to draw similar conclusions in women. A recent pooled analysis of individual patient data has evaluated the long-term safety and efficacy of drug-eluting stents compared to bare-metal stents in a subgroup of female patients with coronary artery disease [Lancet 2013 Dec 7;382(9908):1879]. Testosterone Therapy Associated With Increased Cardiovascular Events in Men With Low Testosterone Levels and High Cardiovascular Risk Testosterone replacement therapy has become increasingly common in recent years and has shown efficacy for improving sexual dysfunction, bone mineral density, exercise capacity, and metabolic parameters in men with androgen deficiency or chronic conditions including heart failure and diabetes. While it may be difficult to minimize bias in an observational study of this type, results from studies like this will often prompt longer follow-up in subsequent randomized trials. [...]data are available, this information and its limitations should be part of the discussion for men considering testosterone replacement therapy.
ISSN:1524-5012