Acute kidney injury in critically ill children: Risk factors and outcomes

Acute kidney injury (AKI) is common in patients in the pediatric intensive care unit (PICU) and is associated with poor outcome. We conducted the present study to determine the incidence, risk factors and outcomes of AKI in the PICU. We collected data retrospectively from case records of children ad...

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Bibliographic Details
Published in:Indian journal of critical care medicine 2014-03, Vol.18 (3), p.129-133
Main Authors: Naik, Shweta, Sharma, Jyoti, Yengkom, Rameshwor, Kalrao, Vijay, Mulay, Atul
Format: Article
Language:English
Subjects:
Acute renal failure
Age
Care and treatment
Critically ill children
Developing countries
Failure
Gender
Hypoxia
Industrialized nations
Intensive care
Kidney diseases
LDCs
Mortality
Multivariate analysis
Older people
Patient outcomes
Pediatric intensive care units
Pediatric research
Pediatrics
Risk factors
Sepsis
Statistics
Studies
Ventilation
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Summary:Acute kidney injury (AKI) is common in patients in the pediatric intensive care unit (PICU) and is associated with poor outcome. We conducted the present study to determine the incidence, risk factors and outcomes of AKI in the PICU. We collected data retrospectively from case records of children admitted to the PICU during one year. We defined and classified AKI according to modified pRIFLE criteria. We used multivariate logistic regression to determine risk factors of AKI and association of AKI with mortality and morbidity. Of the 252 children included in the study, 103 (40.9%) children developed AKI. Of these 103 patients with AKI, 39 (37.9%) patients reached pRIFLE max of Risk, 37 (35.9%) patients reached Injury, and 27 (26.2%) had Failure. Mean Pediatric Risk of Mortality (PRISM III) score at admission was higher in patients with AKI than in controls (P < 0.001).
ISSN:0972-5229
1998-359X
DOI:10.4103/0972-5229.128701