Risk factors for intestinal metaplasia in concomitant gastric and duodenal ulcer disease

The aim of this study was to estimate the prevalence and risk factors of intestinal metaplasia (IM) in concomitant gastric and duodenal ulcer (CGDU) disease by retrospectively reviewing consecutive patients who had undergone esophagogastroduodenal endoscopy. Patients who received the endoscopic diag...

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Bibliographic Details
Published in:Experimental and therapeutic medicine 2014-04, Vol.7 (4), p.929-934
Main Authors: HONG, JUN-BO, XIA, LIANG, ZUO, WEI, WANG, AN-JIANG, XU, SHAN, XIONG, HUI-FANG, CHEN, YOU-XIANG, ZHU, XUAN, LU, NONG-HUA
Format: Article
Language:English
Subjects:
Acids
Biopsy
Care and treatment
Complications and side effects
concomitant gastric and duodenal ulcers
Confidence intervals
Diagnosis
Duodenal ulcer
Endoscopy
Females
Gastric cancer
Gastroesophageal reflux
Health aspects
Helicobacter pylori infection
Infections
intestinal metaplasia
Multivariate analysis
Nausea
Pain
Patients
Risk factors
Stomach cancer
Ulcers
Vomiting
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Summary:The aim of this study was to estimate the prevalence and risk factors of intestinal metaplasia (IM) in concomitant gastric and duodenal ulcer (CGDU) disease by retrospectively reviewing consecutive patients who had undergone esophagogastroduodenal endoscopy. Patients who received the endoscopic diagnosis of CGDU disease were selected for analysis and the recorded demographic, endoscopic, clinical and outcome data, including data on the development of IM, were extracted. Associations of the various parameters with IM were estimated by logistic regression analysis and described by the odds ratio (OR) with a 95% confidence interval (CI). Among the total 204,073 consecutive patients screened, 2,397 (1.2%) were diagnosed with CGDU disease. Following application of the exclusion criteria, a total of 2,149 cases were included in the study. The IM prevalence was 8.4%, represented by 153 mild cases, 26 moderate cases and one severe case. Multivariate analysis identified age ≥50 years (OR=2.606, 95% CI=1.889-3.597, χ2=34.000, P
ISSN:1792-0981
1792-1015
DOI:10.3892/etm.2014.1507