Every which way-nanos gene regulation in echinoderms

Summary Nanos is an essential factor of germ line success in all animals tested. This gene encodes a Zn‐finger RNA‐binding protein that in complex with its partner pumilio binds to and changes the fate of several known transcripts. We summarize here the documented functions of Nanos in several key o...

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Bibliographic Details
Published in:Genesis (New York, N.Y. : 2000) N.Y. : 2000), 2014-03, Vol.52 (3), p.279-286
Main Authors: Oulhen, Nathalie, Wessel, Gary M.
Format: Article
Language:English
Subjects:
Animals
Cell Lineage - physiology
Drosophila Proteins - genetics
Drosophila Proteins - metabolism
Echinodermata - genetics
Echinodermata - metabolism
Echinodermata - physiology
Echinoidea
Gene Expression Regulation - genetics
Gene Expression Regulation - physiology
Germ Cells - metabolism
Germ Cells - physiology
germ line
primordial germ cells
RNA-Binding Proteins - genetics
RNA-Binding Proteins - metabolism
sea star
sea urchin
Species Specificity
starfish
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Summary:Summary Nanos is an essential factor of germ line success in all animals tested. This gene encodes a Zn‐finger RNA‐binding protein that in complex with its partner pumilio binds to and changes the fate of several known transcripts. We summarize here the documented functions of Nanos in several key organisms, and then emphasize echinoderms as a working model for how nanos expression is regulated. Nanos presence outside of the target cells is often detrimental to the animal, and in sea urchins, nanos expression appears to be regulated at every step of transcription, and post‐transcriptional activity, making this gene product exciting, every which way. genesis 52:279–286. © 2013 Wiley Periodicals, Inc.
ISSN:1526-954X
1526-968X
DOI:10.1002/dvg.22737