Valacyclovir associated neurotoxicity in a patient on dialysis

[2] In several studies reported in past [Table 1] [3] it has been shown that occurrence of valacyclovir associated neurotoxicity (VAN) has been common in elderlies, with a daily dose ranging from 500 to 3000 mg/ day, more frequent in CKD patients, treated successfully after discontinuation of drug a...

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Bibliographic Details
Published in:Indian journal of nephrology 2014-03, Vol.24 (2), p.128-129
Main Authors: Singh, N, Shah, H, Aggarwal, N, Jha, L, Behura, S
Format: Article
Language:English
Subjects:
Deoxyribonucleic acid
Diagnosis
DNA
Dosage and administration
Drug dosages
Health aspects
Hemodialysis patients
Letters to Editor
Medical treatment
Neurotoxicity
Neurotoxicity syndromes
NMR
Nuclear magnetic resonance
Prognosis
Risk factors
Valacyclovir
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Summary:[2] In several studies reported in past [Table 1] [3] it has been shown that occurrence of valacyclovir associated neurotoxicity (VAN) has been common in elderlies, with a daily dose ranging from 500 to 3000 mg/ day, more frequent in CKD patients, treated successfully after discontinuation of drug and requiring at least a single hemodialysis. Valacyclovir can pose a diagnostic dilemma for the clinician as herpes zoster encephalitis and VAN share disturbance in sensorium as most frequent manifestation.
ISSN:0971-4065
1998-3662
DOI:10.4103/0971-4065.127915