Progesterone receptor expression in sinonasal leiomyoma: a case report and review of the literature

Leiomyomas are benign myogenic tumors that seldom occur in the sinonasal cavity. They were commonly found in middle-aged adults with a female predominance. Clinical symptoms include nasal obstruction with discharge, nasal bleeding and pain. We describe the case of a 48 year-old woman with a leiomyom...

Full description

Saved in:
Bibliographic Details
Published in:International journal of clinical and experimental pathology 2014-01, Vol.7 (3), p.1224-1228
Main Authors: Tseng, Pao-Yu, Lai, Yu-Shih, Chen, Mu-Kuan, Shen, Ko-Hung
Format: Article
Language:English
Subjects:
Biomarkers, Tumor - analysis
Case Report
Female
Humans
Immunohistochemistry
Leiomyoma - metabolism
Leiomyoma - pathology
Middle Aged
Nose Neoplasms - metabolism
Nose Neoplasms - pathology
Paranasal Sinus Neoplasms - metabolism
Paranasal Sinus Neoplasms - pathology
Receptors, Progesterone - biosynthesis
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Leiomyomas are benign myogenic tumors that seldom occur in the sinonasal cavity. They were commonly found in middle-aged adults with a female predominance. Clinical symptoms include nasal obstruction with discharge, nasal bleeding and pain. We describe the case of a 48 year-old woman with a leiomyoma arising from right inferior nasal turbinate. Transnasal endoscopic excision was performed with satisfied result. The tumor was found to be progesterone receptor positive on immunohistochemical analysis. The clinical findings are addressed with a review of the literature. To the best of our knowledge, this is the third reported case that supports the growth of the tumor may be hormone-dependent.
ISSN:1936-2625