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Asymptomatic bacteriuria in postmenopausal women with diabetes mellitus
An evaluation of efficacy of the management of urinary tract infections by using local forms of Estriol in postmenopausal women with type II diabetes and asymptomatic bacteriuria. The study was conducted in two stages. The first stage: a prospective cross-sectional study to identify patients with as...
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Published in: | Central European journal of urology 2013, Vol.66 (3), p.320-326 |
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container_title | Central European journal of urology |
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creator | Kasyan, George Berketova, Tatiana Y Rogozin, Anton K Pushkar, Dmitry Y |
description | An evaluation of efficacy of the management of urinary tract infections by using local forms of Estriol in postmenopausal women with type II diabetes and asymptomatic bacteriuria.
The study was conducted in two stages. The first stage: a prospective cross-sectional study to identify patients with asymptomatic bacteriuria. During this stage, 414 postmenopausal women with type II diabetes, but without clinical symptoms of urinary tract infection, were investigated. In the second stage, women with asymptomatic bacteriuria (87 women) were randomized to two groups: the first group was the main group receiving 0.5 mg of Estriol as a vaginal cream, the second group was the control group. The study lasted 12 months.
After 12 months of the study, asymptomatic bacteriuria was revealed in 19.4% of women in the group 1 and 68.4% of women in the group 2 (p |
doi_str_mv | 10.5173/ceju.2013.03.art17 |
format | article |
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The study was conducted in two stages. The first stage: a prospective cross-sectional study to identify patients with asymptomatic bacteriuria. During this stage, 414 postmenopausal women with type II diabetes, but without clinical symptoms of urinary tract infection, were investigated. In the second stage, women with asymptomatic bacteriuria (87 women) were randomized to two groups: the first group was the main group receiving 0.5 mg of Estriol as a vaginal cream, the second group was the control group. The study lasted 12 months.
After 12 months of the study, asymptomatic bacteriuria was revealed in 19.4% of women in the group 1 and 68.4% of women in the group 2 (p <0.001), and symptomatic urinary tract infection in 8.3% of women in the group 1 and 18.4% of women in the group 2 (p <0.001). There was no connection revealed between asymptomatic bacteriuria and HbA1с. Using Estriol in group 1 led to an increase in VHI, the appearance of lactobacilli in the vaginal smear, and the decrease of symptom frequency in atrophic vaginitis. In group 2, there were no significant changes revealed.
Usage of local forms of Estriol effectively prevents and decreases the frequency of asymptomatic bacteriuria and urinary tract infection in postmenopausal women suffering with diabetes mellitus.</description><identifier>ISSN: 2080-4806</identifier><identifier>ISSN: 2080-4873</identifier><identifier>EISSN: 2080-4873</identifier><identifier>DOI: 10.5173/ceju.2013.03.art17</identifier><identifier>PMID: 24707373</identifier><language>eng</language><publisher>Poland: Polish Urological Association</publisher><subject>Original Paper</subject><ispartof>Central European journal of urology, 2013, Vol.66 (3), p.320-326</ispartof><rights>Copyright Polish Urological Association 2013</rights><rights>Copyright by Polish Urological Association 2013</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3457-97f57ba9ae135e33f409c0229d1c9c00d11ab28cbc98c25ecc96b427a1c7a81b3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974470/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974470/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,4024,27923,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24707373$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kasyan, George</creatorcontrib><creatorcontrib>Berketova, Tatiana Y</creatorcontrib><creatorcontrib>Rogozin, Anton K</creatorcontrib><creatorcontrib>Pushkar, Dmitry Y</creatorcontrib><title>Asymptomatic bacteriuria in postmenopausal women with diabetes mellitus</title><title>Central European journal of urology</title><addtitle>Cent European J Urol</addtitle><description>An evaluation of efficacy of the management of urinary tract infections by using local forms of Estriol in postmenopausal women with type II diabetes and asymptomatic bacteriuria.
The study was conducted in two stages. The first stage: a prospective cross-sectional study to identify patients with asymptomatic bacteriuria. During this stage, 414 postmenopausal women with type II diabetes, but without clinical symptoms of urinary tract infection, were investigated. In the second stage, women with asymptomatic bacteriuria (87 women) were randomized to two groups: the first group was the main group receiving 0.5 mg of Estriol as a vaginal cream, the second group was the control group. The study lasted 12 months.
After 12 months of the study, asymptomatic bacteriuria was revealed in 19.4% of women in the group 1 and 68.4% of women in the group 2 (p <0.001), and symptomatic urinary tract infection in 8.3% of women in the group 1 and 18.4% of women in the group 2 (p <0.001). There was no connection revealed between asymptomatic bacteriuria and HbA1с. Using Estriol in group 1 led to an increase in VHI, the appearance of lactobacilli in the vaginal smear, and the decrease of symptom frequency in atrophic vaginitis. In group 2, there were no significant changes revealed.
Usage of local forms of Estriol effectively prevents and decreases the frequency of asymptomatic bacteriuria and urinary tract infection in postmenopausal women suffering with diabetes mellitus.</description><subject>Original Paper</subject><issn>2080-4806</issn><issn>2080-4873</issn><issn>2080-4873</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><recordid>eNpdkU9LAzEQxYMoVmq_gAdZ8OKlNX-b3YtQilah4EXPYTZNbcruZk2yln57U1uLmksmzJuXefwQuiJ4JIhkd9qsuxHFhI0wG4GPRJ6gC4pzPOS5ZKfHGo97aBDCGqczzvlYiHPUo1xiySS7QLNJ2NZtdDVEq7MSdDTedt5CZpusdSHWpnEtdAGqbOPSI9vYuMoWFkoTTchqU1U2duESnS2hCmZwuPvo7fHhdfo0nL_MnqeT-VAzLuSwkEshSyjAECYMY0uOC40pLRZEpwIvCIGS5rrURa6pMFoX45JTCURLyEnJ-uh-79t2ZW0W2jTRQ6Vab2vwW-XAqr-dxq7Uu_tUrJA8pU4GtwcD7z46E6KqbdApBTTGdUERQXj6UHCSpDf_pGvX-SbFSypMaM4l26noXqW9C8Gb5XEZgtUOldqhUjtUCjP1jSoNXf-OcRz5AcO-AE2qkpE</recordid><startdate>2013</startdate><enddate>2013</enddate><creator>Kasyan, George</creator><creator>Berketova, Tatiana Y</creator><creator>Rogozin, Anton K</creator><creator>Pushkar, Dmitry Y</creator><general>Polish Urological Association</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>BYOGL</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>2013</creationdate><title>Asymptomatic bacteriuria in postmenopausal women with diabetes mellitus</title><author>Kasyan, George ; Berketova, Tatiana Y ; Rogozin, Anton K ; Pushkar, Dmitry Y</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3457-97f57ba9ae135e33f409c0229d1c9c00d11ab28cbc98c25ecc96b427a1c7a81b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Original Paper</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kasyan, George</creatorcontrib><creatorcontrib>Berketova, Tatiana Y</creatorcontrib><creatorcontrib>Rogozin, Anton K</creatorcontrib><creatorcontrib>Pushkar, Dmitry Y</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest_Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central</collection><collection>East Europe, Central Europe Database</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Central European journal of urology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kasyan, George</au><au>Berketova, Tatiana Y</au><au>Rogozin, Anton K</au><au>Pushkar, Dmitry Y</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Asymptomatic bacteriuria in postmenopausal women with diabetes mellitus</atitle><jtitle>Central European journal of urology</jtitle><addtitle>Cent European J Urol</addtitle><date>2013</date><risdate>2013</risdate><volume>66</volume><issue>3</issue><spage>320</spage><epage>326</epage><pages>320-326</pages><issn>2080-4806</issn><issn>2080-4873</issn><eissn>2080-4873</eissn><abstract>An evaluation of efficacy of the management of urinary tract infections by using local forms of Estriol in postmenopausal women with type II diabetes and asymptomatic bacteriuria.
The study was conducted in two stages. The first stage: a prospective cross-sectional study to identify patients with asymptomatic bacteriuria. During this stage, 414 postmenopausal women with type II diabetes, but without clinical symptoms of urinary tract infection, were investigated. In the second stage, women with asymptomatic bacteriuria (87 women) were randomized to two groups: the first group was the main group receiving 0.5 mg of Estriol as a vaginal cream, the second group was the control group. The study lasted 12 months.
After 12 months of the study, asymptomatic bacteriuria was revealed in 19.4% of women in the group 1 and 68.4% of women in the group 2 (p <0.001), and symptomatic urinary tract infection in 8.3% of women in the group 1 and 18.4% of women in the group 2 (p <0.001). There was no connection revealed between asymptomatic bacteriuria and HbA1с. Using Estriol in group 1 led to an increase in VHI, the appearance of lactobacilli in the vaginal smear, and the decrease of symptom frequency in atrophic vaginitis. In group 2, there were no significant changes revealed.
Usage of local forms of Estriol effectively prevents and decreases the frequency of asymptomatic bacteriuria and urinary tract infection in postmenopausal women suffering with diabetes mellitus.</abstract><cop>Poland</cop><pub>Polish Urological Association</pub><pmid>24707373</pmid><doi>10.5173/ceju.2013.03.art17</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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title | Asymptomatic bacteriuria in postmenopausal women with diabetes mellitus |
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