Longitudinal changes in calcaneal quantitative ultrasound measures during childhood

Summary This longitudinal study examined how calcaneal quantitative ultrasound (QUS) measures change during childhood while taking into account skeletal maturation, body mass index (BMI), and physical activity. The study reported sex differences in QUS growth curves and an inverse relationship betwe...

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Bibliographic Details
Published in:Osteoporosis international 2011-08, Vol.22 (8), p.2295-2305
Main Authors: Lee, M., Nahhas, R. W., Choh, A. C., Demerath, E. W., Duren, D. L., Chumlea, W. C., Sherwood, R. J., Towne, B., Siervogel, R. M., Czerwinski, S. A.
Format: Article
Language:English
Subjects:
Adipose tissue
Adiposity
Adolescence
Age
Age Determination by Skeleton
Aging - physiology
Biological and medical sciences
Body Mass Index
Bone Density - physiology
Bones
Calcaneus
Calcaneus - diagnostic imaging
Calcaneus - growth & development
Calcaneus - physiology
Child
Children
Children & youth
Diseases of the osteoarticular system
Endocrinology
Exercise
Female
Gender differences
Growth curves
Humans
Longitudinal Studies
Male
Medical sciences
Medicine
Medicine & Public Health
Motor Activity - physiology
Original Article
Orthopedics
Osteoporosis
Osteoporosis. Osteomalacia. Paget disease
Physical activity
Rheumatology
Sex Characteristics
Sex differences
Sports - physiology
Statistical analysis
Statistics
Ultrasonic imaging
Ultrasonography
Ultrasound
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Summary:Summary This longitudinal study examined how calcaneal quantitative ultrasound (QUS) measures change during childhood while taking into account skeletal maturation, body mass index (BMI), and physical activity. The study reported sex differences in QUS growth curves and an inverse relationship between BMI and speed of sound (SOS) measures. Introduction The aim of this study was to examine how calcaneal QUS parameters change over time during childhood and to determine what factors influence these changes. Methods The study sample consisted of a total of 192 Caucasian children participating in the Fels Longitudinal Study. A total of 548 calcaneal broadband ultrasound attenuation (BUA) and SOS observations were obtained between the ages of 7.6 and 18 years. The best fitting growth curves were determined using statistical methods for linear mixed effect models. Results There are significant sex differences in the pattern of change in QUS parameters ( p  
ISSN:0937-941X
1433-2965
DOI:10.1007/s00198-010-1458-0