Radiation-induced malignant fibrous histiocytoma of the occipital: a case report

Malignant fibrous histiocytoma (MFH) is a rare neoplasm exhibiting a propensity for aggressive clinical behavior. Effective treatment modality is surgical resection with wide margins, but its rate of recurrence and metastasis is still high. Early detection and complete excision of the tumor is neces...

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Bibliographic Details
Published in:World journal of surgical oncology 2014-04, Vol.12 (1), p.98-98
Main Authors: Zhang, Guo-Bin, Li, Jian, Zhang, Peng-Fei, Han, Li-Jiang, Zhang, Jun-Ting
Format: Article
Language:English
Subjects:
Care and treatment
Case Report
Complications and side effects
CT imaging
Development and progression
Diagnosis
Female
Histiocytoma, Malignant Fibrous - diagnosis
Histiocytoma, Malignant Fibrous - etiology
Histiocytoma, Malignant Fibrous - surgery
Humans
Magnetic Resonance Imaging
Medulloblastoma - complications
Medulloblastoma - radiotherapy
Metastasis
Middle Aged
Neoplasms, Second Primary - diagnosis
Neoplasms, Second Primary - etiology
Neoplasms, Second Primary - surgery
Occipital Bone - radiation effects
Patient outcomes
Prognosis
Radiation
Radiotherapy
Radiotherapy - adverse effects
Sarcoma - diagnosis
Sarcoma - etiology
Sarcoma - surgery
Tomography, X-Ray Computed
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Summary:Malignant fibrous histiocytoma (MFH) is a rare neoplasm exhibiting a propensity for aggressive clinical behavior. Effective treatment modality is surgical resection with wide margins, but its rate of recurrence and metastasis is still high. Early detection and complete excision of the tumor is necessary. A MFH of the occipital developed in a 51-year-old woman eight years after surgery and radiation for medulloblastoma of the cerebellar vermis. The secondary neoplasm arose at the site of tumor resection within the irradiated field, and was resected. The development of sarcomas is a recognized complication of radiation therapy. The final diagnosis after the operation was MFH. Radiation-induced sarcoma (RIS) is well known, but radiation-induced MFH is relatively rare in the head and neck region, especially in the occipital. The imaging findings are not diagnosis specific, but strict follow-up within the radiation field by computerized tomography (CT) and magnetic resonance imaging (MRI) and appreciation of the expected latency period may help in providing the diagnosis of RIS.
ISSN:1477-7819
1477-7819
DOI:10.1186/1477-7819-12-98