Propofol or Thiopental sodium in patients undergoing reproductive assisted technologies: Differences in hemodynamic recovery and outcome of oocyte retrieval: A randomized clinical trial

Background: Thiopental sodium and Propofol are two widely-used drugs in the induction of anesthesia in assisted reproductive technology (ART). However, the side effects and outcome of recovery from anesthesia of these drugs on ART have not been identified yet. Objective: This study aimed at investig...

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Bibliographic Details
Published in:Iranian journal of reproductive medicine 2014-01, Vol.12 (1), p.77-82
Main Authors: Jarahzadeh, Mohammad Hossein, Jouya, Reza, Mousavi, Fatemeh Sadat, Dehghan-tezerjani, Mohammad, Behdad, Shekoofa, Soltani, Hamid Reza
Format: Article
Language:English
Subjects:
Assisted reproductive technology
Propofol
Short Communication
Thiopental sodium
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Summary:Background: Thiopental sodium and Propofol are two widely-used drugs in the induction of anesthesia in assisted reproductive technology (ART). However, the side effects and outcome of recovery from anesthesia of these drugs on ART have not been identified yet. Objective: This study aimed at investigating the side effects and hemodynamic effects of using thiopental sodium and propofal as well as effects of these drugs on pregnancy outcome in ART cycles. Materials and Methods: In this double blinded) randomized controlled trial, 90 woman candidate for ART were randomly divided into two groups. 47 patients received Propofol (2.5 mg/kg) and 43 patients received thiopental (5mg/kg) for anesthesia induction. The entry hemodynamic parameters of the patients were documented. During the anesthesia process, hemodynamic parameters were checked at five-minute intervals. Results: The results of the study showed a statistically significant difference between two groups in terms of their response to verbal stimulation (p
ISSN:1680-6433
2008-2177