A Comparison of Measured and Calculated Free 25(OH) Vitamin D Levels in Clinical Populations

Objective: Our goal was to compare direct quantitation of circulating free 25-hydroxyvitamin D (25(OH)D)levels to calculated free 25(OH)D levels and their relationships to intact PTH (iPTH), a biomarker of 25(OH)D effect, in humans with a range of clinical conditions. Patients and Methods: Serum sam...

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Bibliographic Details
Published in:The journal of clinical endocrinology and metabolism 2014-05, Vol.99 (5), p.1631-1637
Main Authors: Schwartz, J. B, Lai, J, Lizaola, B, Kane, L, Markova, S, Weyland, P, Terrault, N. A, Stotland, N, Bikle, D
Format: Article
Language:English
Subjects:
Adult
Aged
Endocrine Care
Female
Humans
Liver Cirrhosis - blood
Male
Middle Aged
Pregnancy
Vitamin D - analogs & derivatives
Vitamin D - blood
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Summary:Objective: Our goal was to compare direct quantitation of circulating free 25-hydroxyvitamin D (25(OH)D)levels to calculated free 25(OH)D levels and their relationships to intact PTH (iPTH), a biomarker of 25(OH)D effect, in humans with a range of clinical conditions. Patients and Methods: Serum samples and clinical data were collected from 155 people: 111 without cirrhosis or pregnancy (comparison group), 24 cirrhotic patients with albumin
ISSN:0021-972X
1945-7197
DOI:10.1210/jc.2013-3874