CEBPA-CEBPG axis as a novel promising therapeutic target in acute myeloid leukemia

Disruption of normal differentiation is an important link in tumorigen-esis, but understanding the molecular mechanisms underlying this process is still limited. Acute myeloid leukemia （AML） is characterized by an accumula- tion of immature myeloid precursor cells in the bone marrow, which has been...

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Bibliographic Details
Published in:Acta pharmacologica Sinica 2013-02, Vol.34 (2), p.185-186
Main Author: Lou, Yin-jun
Format: Article
Language:English
Subjects:
AML
Biomedical and Life Sciences
Biomedicine
Immunology
Internal Medicine
Medical Microbiology
Pharmacology/Toxicology
Research Highlight
Vaccine
分子机制
前体细胞
急性
治疗
白血病
粒细胞
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Summary:Disruption of normal differentiation is an important link in tumorigen-esis, but understanding the molecular mechanisms underlying this process is still limited. Acute myeloid leukemia （AML） is characterized by an accumula- tion of immature myeloid precursor cells in the bone marrow, which has been extensively used as a model for studying.
ISSN:1671-4083
1745-7254
DOI:10.1038/aps.2012.191