The Acute Transcriptomic and Proteomic Response of HC-04 Hepatoma Cells to Hepatocyte Growth Factor and its Implications for Plasmodium falciparum Sporozoite Invasion

The routine study of human malaria liver-stage biology in vitro is hampered by low infection efficiency of human hepatocellular carcinoma (HCC) lines (

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Bibliographic Details
Published in:Molecular & cellular proteomics 2014-05, Vol.13 (5), p.1153-1164
Main Authors: Tao, Dingyin, King, Jonas G., Tweedell, Rebecca E., Jost, Philipp J., Boddey, Justin A., Dinglasan, Rhoel R.
Format: Article
Language:English
Subjects:
Cell Line, Tumor - cytology
Cell Line, Tumor - parasitology
Epithelial-Mesenchymal Transition
Gene Expression Profiling
Hep G2 Cells
Hepatocyte Growth Factor - metabolism
Hepatocytes - parasitology
Humans
Malaria, Falciparum - metabolism
Malaria, Falciparum - parasitology
Models, Biological
Plasmodium falciparum - growth & development
Plasmodium falciparum - physiology
Protein Transport
Proteomics
Protozoan Proteins - metabolism
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Description
Summary:The routine study of human malaria liver-stage biology in vitro is hampered by low infection efficiency of human hepatocellular carcinoma (HCC) lines (
ISSN:1535-9476
1535-9484
DOI:10.1074/mcp.M113.035584