Aging and chronic kidney disease: the impact on physical function and cognition

Evidence has recently been building that the presence of chronic kidney disease (CKD) is an independent contributor to decline in physical and cognitive functions in older adults. CKD affects 45% of persons older than 70 years of age and can double the risk for physical impairment, cognitive dysfunc...

Full description

Saved in:
Bibliographic Details
Published in:The journals of gerontology. Series A, Biological sciences and medical sciences Biological sciences and medical sciences, 2014-03, Vol.69 (3), p.315-322
Main Authors: Anand, Shuchi, Johansen, Kirsten L, Kurella Tamura, Manjula
Format: Article
Language:English
Subjects:
Aging
Aging - physiology
Cognition & reasoning
Cognition - physiology
Cognition Disorders - etiology
Disabled Persons
Frailty
Humans
Kidney diseases
Motor Activity - physiology
Older people
Renal Insufficiency, Chronic - physiopathology
Review
Risk factors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Evidence has recently been building that the presence of chronic kidney disease (CKD) is an independent contributor to decline in physical and cognitive functions in older adults. CKD affects 45% of persons older than 70 years of age and can double the risk for physical impairment, cognitive dysfunction, and frailty. To increase awareness of this relatively new concept of CKD as a risk factor for accelerated aging, we review studies on the association of CKD with physical function, frailty, and cognitive function. We also present a summary of the proposed mechanisms for these associations.
ISSN:1079-5006
1758-535X
DOI:10.1093/gerona/glt109