Prevalence and determinants of osteoporosis in patients with type 1 and type 2 diabetes mellitus

Increased risk of osteoporosis and its clinical significance in patients with diabetes is controversial. We analyze osteoporosis prevalence and determinants of bone mineral density (BMD) in patients with type 1 and 2 diabetes. Three hundred and ninety-eight consecutive diabetic patients from a singl...

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Bibliographic Details
Published in:BMC endocrine disorders 2014-04, Vol.14 (1), p.33-33, Article 33
Main Authors: Leidig-Bruckner, Gudrun, Grobholz, Sonja, Bruckner, Thomas, Scheidt-Nave, Christa, Nawroth, Peter, Schneider, Jochen G
Format: Article
Language:English
Subjects:
Absorptiometry, Photon
Adolescent
Adult
Aged
Aged, 80 and over
Analysis
Bone Density
Case-Control Studies
Cross-Sectional Studies
Diabetes Mellitus, Type 1 - complications
Diabetes Mellitus, Type 1 - physiopathology
Diabetes Mellitus, Type 2 - complications
Diabetes Mellitus, Type 2 - physiopathology
Epidemiology
Female
Femur Neck - physiopathology
Follow-Up Studies
Fractures, Bone - epidemiology
Fractures, Bone - etiology
Fractures, Bone - pathology
Glycosylated hemoglobin
Humans
Hyperglycemia
Insulin
Lumbar Vertebrae - physiopathology
Male
Medical research
Medicine, Experimental
Middle Aged
Older people
Osteoporosis
Osteoporosis - epidemiology
Osteoporosis - etiology
Osteoporosis - pathology
Prevalence
Prognosis
Risk Factors
Statistics
Young Adult
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Summary:Increased risk of osteoporosis and its clinical significance in patients with diabetes is controversial. We analyze osteoporosis prevalence and determinants of bone mineral density (BMD) in patients with type 1 and 2 diabetes. Three hundred and ninety-eight consecutive diabetic patients from a single outpatient clinic received a standardized questionnaire on osteoporosis risk factors, and were evaluated for diabetes-related complications, HbA1c levels, and lumbar spine (LS) and femoral neck (FN) BMD. Of these, 139 (71 men, 68 women) type 1 and 243 (115 men, 128 women) type 2 diabetes patients were included in the study. BMD (T-scores and values adjusted for age, BMI and duration of disease) was compared between patient groups and between patients with type 2 diabetes and population-based controls (255 men, 249 women). For both genders, adjusted BMD was not different between the type 1 and type 2 diabetes groups but was higher in the type 2 group compared with controls (p 
ISSN:1472-6823
1472-6823
DOI:10.1186/1472-6823-14-33