Characterization of speckle in lung images acquired with a benchtop in-line x-ray phase-contrast system

We investigate the manifestation of speckle in propagation-based x-ray phase-contrast imaging of mouse lungs in situ by use of a benchtop imager. The key contributions of the work are the demonstration that lung speckle can be observed by use of a benchtop imaging system employing a polychromatic tu...

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Bibliographic Details
Published in:Physics in medicine & biology 2013-06, Vol.58 (12), p.4237-4253
Main Authors: Garson, A B, Izaguirre, E W, Price, S G, Anastasio, M A
Format: Article
Language:English
Subjects:
Animals
Color
Image Processing, Computer-Assisted - methods
Lung - diagnostic imaging
Mice
Tomography, X-Ray Computed - methods
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Summary:We investigate the manifestation of speckle in propagation-based x-ray phase-contrast imaging of mouse lungs in situ by use of a benchtop imager. The key contributions of the work are the demonstration that lung speckle can be observed by use of a benchtop imaging system employing a polychromatic tube-source and a systematic experimental investigation of how the texture of the speckle pattern depends on the parameters of the imaging system. Our analyses consists of image texture characterization based on the statistical properties of pixel intensity values.
ISSN:0031-9155
1361-6560
DOI:10.1088/0031-9155/58/12/4237