False-positive rapid plasma reagin testing in patients with acute Plasmodium vivax malaria: A case control study

Summary Non-treponemal tests such as the rapid plasma reagin (RPR) assay are mainstays of syphilis diagnosis, but false-positive tests are common. We identified false-positive RPR titers in 8.2% of patients with malaria due to Plasmodium vivax in northern Peru. Similar rates were not detected in pat...

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Bibliographic Details
Published in:Travel medicine and infectious disease 2014-05, Vol.12 (3), p.268-273
Main Authors: Maves, Ryan C, Dean, Katherine, Gadea, Nilda, Halsey, Eric S, Graf, Paul C.F, Lescano, Andres G
Format: Article
Language:English
Subjects:
Acute Disease
Adult
Case-Control Studies
Demography
Diagnostic test
False Positive Reactions
Female
Fever of Unknown Origin - etiology
Humans
Infectious Disease
Malaria, Vivax - diagnosis
Male
Middle Aged
Peru
Plasmodium vivax
Plasmodium vivax - isolation & purification
Reagins - blood
Syphilis
Syphilis - complications
Syphilis Serodiagnosis
Time Factors
Treponema pallidum
Vivax malaria
Young Adult
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Summary:Summary Non-treponemal tests such as the rapid plasma reagin (RPR) assay are mainstays of syphilis diagnosis, but false-positive tests are common. We identified false-positive RPR titers in 8.2% of patients with malaria due to Plasmodium vivax in northern Peru. Similar rates were not detected in patients with other acute febrile illnesses.
ISSN:1477-8939
1873-0442
DOI:10.1016/j.tmaid.2013.10.010