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False-positive rapid plasma reagin testing in patients with acute Plasmodium vivax malaria: A case control study

Summary Non-treponemal tests such as the rapid plasma reagin (RPR) assay are mainstays of syphilis diagnosis, but false-positive tests are common. We identified false-positive RPR titers in 8.2% of patients with malaria due to Plasmodium vivax in northern Peru. Similar rates were not detected in pat...

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Published in:	Travel medicine and infectious disease 2014-05, Vol.12 (3), p.268-273
Main Authors:	Maves, Ryan C, Dean, Katherine, Gadea, Nilda, Halsey, Eric S, Graf, Paul C.F, Lescano, Andres G
Format:	Article
Language:	English
Subjects:	Acute Disease Adult Case-Control Studies Demography Diagnostic test False Positive Reactions Female Fever of Unknown Origin - etiology Humans Infectious Disease Malaria, Vivax - diagnosis Male Middle Aged Peru Plasmodium vivax Plasmodium vivax - isolation & purification Reagins - blood Syphilis Syphilis - complications Syphilis Serodiagnosis Time Factors Treponema pallidum Vivax malaria Young Adult
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creator	Maves, Ryan C Dean, Katherine Gadea, Nilda Halsey, Eric S Graf, Paul C.F Lescano, Andres G
description	Summary Non-treponemal tests such as the rapid plasma reagin (RPR) assay are mainstays of syphilis diagnosis, but false-positive tests are common. We identified false-positive RPR titers in 8.2% of patients with malaria due to Plasmodium vivax in northern Peru. Similar rates were not detected in patients with other acute febrile illnesses.
doi_str_mv	10.1016/j.tmaid.2013.10.010
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subjects	Acute Disease Adult Case-Control Studies Demography Diagnostic test False Positive Reactions Female Fever of Unknown Origin - etiology Humans Infectious Disease Malaria, Vivax - diagnosis Male Middle Aged Peru Plasmodium vivax Plasmodium vivax - isolation & purification Reagins - blood Syphilis Syphilis - complications Syphilis Serodiagnosis Time Factors Treponema pallidum Vivax malaria Young Adult
title	False-positive rapid plasma reagin testing in patients with acute Plasmodium vivax malaria: A case control study
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