Successful surgical treatment of extrahepatic biliary papillomatosis diagnosed with endoscopic retrograde cholangiopancreatography: a case report

Biliary papillomatosis is a condition characterized by multiple papillary tumors of variable distribution and extent within the biliary tract. Papillary carcinoma can develop in these lesions. It is a rare biliary pathological entity and its clinical features and outcome are not well known. We exper...

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Bibliographic Details
Published in:Journal of medical case reports 2014-05, Vol.8 (1), p.148-148, Article 148
Main Authors: Adioui, Tarik, Seddik, Hassan, Baba, Hicham, Slioui, Badr, Ali, Abdelmounaim Ait, El Hamdi, Fatima Zohra, Benkirane, Ahmed, Zentar, Aziz
Format: Article
Language:English
Subjects:
Bile Duct Neoplasms - complications
Bile Duct Neoplasms - diagnosis
Bile Duct Neoplasms - surgery
Bile Ducts, Extrahepatic - surgery
Case Report
Case studies
Cholangiopancreatography, Endoscopic Retrograde
Health aspects
Humans
Jaundice, Obstructive - etiology
Male
Middle Aged
Papilloma - complications
Papilloma - diagnosis
Papilloma - surgery
Phosphatases
Treatment Outcome
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Summary:Biliary papillomatosis is a condition characterized by multiple papillary tumors of variable distribution and extent within the biliary tract. Papillary carcinoma can develop in these lesions. It is a rare biliary pathological entity and its clinical features and outcome are not well known. We experienced a case of biliary papillomatosis in a 51-year-old North African man who presented with obstructive jaundice. Laboratory tests showed elevated bilirubin, alkaline phosphatase and gamma-glutamyl transpeptidase levels. Imaging (ultrasound and magnetic resonance imaging) was suggestive of Klatskin tumor associated to common bile duct stones. After endoscopic retrograde cholangiopancreatography, a balloon sweep retrieved friable tissue from his bile ducts. Histology demonstrated papillary adenomatous proliferation showing high-grade dysplasia and he was referred for surgical management. Although biliary papillomatosis is rare, it is a premalignant condition that should be well known and considered in all diagnoses of obstructive jaundice. We report a new case of biliary papillomatosis and highlight the contribution of endoscopic retrograde cholangiopancreatography in the diagnosis of this condition.
ISSN:1752-1947
1752-1947
DOI:10.1186/1752-1947-8-148