The potential clinical applications and prospects of microRNAs in lung cancer

Lung cancer is the major cause of cancer deaths worldwide due to its late diagnosis and poor outcome. Understanding genomic medicine may widen our vision into the oncogenesis of lung cancer and may open the door to improvements in the clinical management of lung cancer. It is well known that almost...

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Bibliographic Details
Published in:OncoTargets and therapy 2014-01, Vol.7, p.901-906
Main Authors: Gao, Ying, Gao, Fei, Ma, Jin-Lu, Sun, Wen-Ze, Song, Li-Ping
Format: Article
Language:English
Subjects:
Analysis
biomarker
Care and treatment
chemotherapy
Gene expression
Genetic aspects
Health aspects
Lung cancer
MicroRNA
radiotherapy
Review
Risk factors
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Summary:Lung cancer is the major cause of cancer deaths worldwide due to its late diagnosis and poor outcome. Understanding genomic medicine may widen our vision into the oncogenesis of lung cancer and may open the door to improvements in the clinical management of lung cancer. It is well known that almost half of all genes are regulated by microRNAs (miRNAs). This review focuses on the role of miRNAs in lung cancer and also touches on the value of miRNA-based novel therapies for lung cancers.
ISSN:1178-6930
1178-6930
DOI:10.2147/OTT.S62227