The consequences of sudden fluid shifts on body composition in critically ill patients

Estimation of body composition as fat-free mass (FFM) is subjected to many variations caused by injury and stress conditions in the intensive care unit (ICU). Body cell mass (BCM), the metabolically active part of FFM, is reported to be more specifically correlated to changes in nutritional status....

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Bibliographic Details
Published in:Critical care (London, England) England), 2014-03, Vol.18 (2), p.R49-R49, Article R49
Main Authors: Ismael, Sophie, Savalle, Magali, Trivin, Claire, Gillaizeau, Florence, D'Auzac, Christian, Faisy, Christophe
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Analysis
Body Composition - physiology
Critical Illness - therapy
Female
Fluid Shifts - physiology
Health aspects
Hospital patients
Humans
Intensive Care Units - trends
Male
Middle Aged
Physiological aspects
Prospective Studies
Renal Dialysis - adverse effects
Renal Dialysis - trends
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Summary:Estimation of body composition as fat-free mass (FFM) is subjected to many variations caused by injury and stress conditions in the intensive care unit (ICU). Body cell mass (BCM), the metabolically active part of FFM, is reported to be more specifically correlated to changes in nutritional status. Bedside estimation of BCM could help to provide more valuable markers of nutritional status and may promote understanding of metabolic consequences of energy deficit in the ICU patients. We aimed to quantify BCM, water compartments and FFM by methods usable at the bedside for evaluating the impact of sudden and massive fluid shifts on body composition in ICU patients. We conducted a prospective experimental study over an 6 month-period in a 18-bed ICU. Body composition of 31 consecutive hemodynamically stable patients requiring acute renal replacement therapy for fluid overload (ultrafiltration ≥5% body weight) was investigated before and after the hemodialysis session. Intra-(ICW) and extracellular (ECW) water volumes were calculated from the raw values of the low- and high-frequency resistances measured by multi-frequency bioelectrical impedance. BCM was assessed by a calculated method recently developed for ICU patients. FFM was derived from BCM and ECW. Intradialytic weight loss was 3.8 ± 0.8 kg. Percentage changes of ECW (-7.99 ± 4.60%) and of ICW (-7.63 ± 5.11%) were similar, resulting ECW/ICW ratio constant (1.26 ± 0.20). The fall of FFM (-2.24 ± 1.56 kg, -4.43 ± 2.65%) was less pronounced than the decrease of ECW (P 
ISSN:1364-8535
1466-609X
1364-8535
DOI:10.1186/cc13794