Evidence of natural Wolbachia infections in field populations of Anopheles gambiae

Wolbachia are maternally transmitted intracellular bacteria that invade insect populations by manipulating their reproduction and immunity and thus limiting the spread of numerous human pathogens. Experimental Wolbachia infections can reduce Plasmodium numbers in Anopheles mosquitoes in the laborato...

Full description

Saved in:
Bibliographic Details
Published in:Nature communications 2014-06, Vol.5 (1), p.3985, Article 3985
Main Authors: Baldini, Francesco, Segata, Nicola, Pompon, Julien, Marcenac, Perrine, Robert Shaw, W., Dabiré, Roch K., Diabaté, Abdoulaye, Levashina, Elena A., Catteruccia, Flaminia
Format: Article
Language:English
Subjects:
45
631/158/855
631/326/417
692/699/255/1629
Animal biology
Animals
Anopheles
Anopheles - microbiology
Burkina Faso
Ecology, environment
Female
Gram-Negative Bacterial Infections
Gram-Negative Bacterial Infections - microbiology
Gram-Negative Bacterial Infections - transmission
Humanities and Social Sciences
Life Sciences
Male
Mosquito Control
multidisciplinary
Phylogeny
RNA, Ribosomal, 16S
RNA, Ribosomal, 16S - genetics
Science
Science (multidisciplinary)
Symbiosis
Veterinary medicine and animal Health
Wolbachia
Wolbachia - genetics
Wolbachia - isolation & purification
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c542t-854b7e7a93fff93a5beb7e825e74e56fbfc3e2d5c3182bceba44b72bbfc0e71d3
cites cdi_FETCH-LOGICAL-c542t-854b7e7a93fff93a5beb7e825e74e56fbfc3e2d5c3182bceba44b72bbfc0e71d3
container_end_page
container_issue 1
container_start_page 3985
container_title Nature communications
container_volume 5
creator Baldini, Francesco
Segata, Nicola
Pompon, Julien
Marcenac, Perrine
Robert Shaw, W.
Dabiré, Roch K.
Diabaté, Abdoulaye
Levashina, Elena A.
Catteruccia, Flaminia
description Wolbachia are maternally transmitted intracellular bacteria that invade insect populations by manipulating their reproduction and immunity and thus limiting the spread of numerous human pathogens. Experimental Wolbachia infections can reduce Plasmodium numbers in Anopheles mosquitoes in the laboratory, however, natural Wolbachia infections in field anophelines have never been reported. Here we show evidence of Wolbachia infections in Anopheles gambiae in Burkina Faso, West Africa. Sequencing of the 16S rRNA gene identified Wolbachia sequences in both female and male germlines across two seasons, and determined that these sequences are vertically transmitted from mother to offspring. Whole-genome sequencing of positive samples suggests that the genetic material identified in An. gambiae belongs to a novel Wolbachia strain, related to but distinct from strains infecting other arthropods. The evidence of Wolbachia infections in natural Anopheles populations promotes further investigations on the possible use of natural Wolbachia – Anopheles associations to limit malaria transmission. Wolbachia bacteria live within the cells of many insect species, manipulating their hosts’ reproduction and immune responses. Here, the authors show that these microbes also infect wild populations of malaria-spreading Anopheles mosquitoes, supporting a potential use of Wolbachia to limit malaria transmission.
doi_str_mv 10.1038/ncomms4985
format article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4059924</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3326449131</sourcerecordid><originalsourceid>FETCH-LOGICAL-c542t-854b7e7a93fff93a5beb7e825e74e56fbfc3e2d5c3182bceba44b72bbfc0e71d3</originalsourceid><addsrcrecordid>eNplkd9rFDEQx4NYbDn74h8gC75o5TQ_b5MX4SitFQ4EUXwMSXZyl7KbrJvdA_97c2xtr21eMpn5zHcmMwi9IfgTwUx-ji51XeZKihfojGJOlqSm7OWRfYrOc77F5TBFJOev0CnlCguiyBn6cbUPDUQHVfJVNOM0mLb6nVpr3C6YKkQPbgwp5mJWPkDbVH3qp9bMzpK0jqnfQQu52prOBgOv0Yk3bYbzu3uBfl1f_by8WW6-f_12ud4sneB0XErBbQ21Ucx7r5gRFspbUgE1B7Hy1jsGtBGOEUmtA2t4SaC2-DHUpGEL9GXW7SfbQeMgjqV53Q-hM8NfnUzQjyMx7PQ27TXHQinKi8CHWWD3JO1mvdEHH2ZU4hWRe1LY93fFhvRngjzqLmQHbWsipClrIhjnNSdlyAv07gl6m6YhllEcKKpqrFayUBcz5YaU8wD-vgOC9WGz-mGzBX57_NV79P8eC_BxBnIJxS0MRzWfy_0DCbKvhA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1532970968</pqid></control><display><type>article</type><title>Evidence of natural Wolbachia infections in field populations of Anopheles gambiae</title><source>Publicly Available Content Database</source><source>Nature</source><source>PubMed Central</source><source>Springer Nature - nature.com Journals - Fully Open Access</source><creator>Baldini, Francesco ; Segata, Nicola ; Pompon, Julien ; Marcenac, Perrine ; Robert Shaw, W. ; Dabiré, Roch K. ; Diabaté, Abdoulaye ; Levashina, Elena A. ; Catteruccia, Flaminia</creator><creatorcontrib>Baldini, Francesco ; Segata, Nicola ; Pompon, Julien ; Marcenac, Perrine ; Robert Shaw, W. ; Dabiré, Roch K. ; Diabaté, Abdoulaye ; Levashina, Elena A. ; Catteruccia, Flaminia</creatorcontrib><description>Wolbachia are maternally transmitted intracellular bacteria that invade insect populations by manipulating their reproduction and immunity and thus limiting the spread of numerous human pathogens. Experimental Wolbachia infections can reduce Plasmodium numbers in Anopheles mosquitoes in the laboratory, however, natural Wolbachia infections in field anophelines have never been reported. Here we show evidence of Wolbachia infections in Anopheles gambiae in Burkina Faso, West Africa. Sequencing of the 16S rRNA gene identified Wolbachia sequences in both female and male germlines across two seasons, and determined that these sequences are vertically transmitted from mother to offspring. Whole-genome sequencing of positive samples suggests that the genetic material identified in An. gambiae belongs to a novel Wolbachia strain, related to but distinct from strains infecting other arthropods. The evidence of Wolbachia infections in natural Anopheles populations promotes further investigations on the possible use of natural Wolbachia – Anopheles associations to limit malaria transmission. Wolbachia bacteria live within the cells of many insect species, manipulating their hosts’ reproduction and immune responses. Here, the authors show that these microbes also infect wild populations of malaria-spreading Anopheles mosquitoes, supporting a potential use of Wolbachia to limit malaria transmission.</description><identifier>ISSN: 2041-1723</identifier><identifier>EISSN: 2041-1723</identifier><identifier>DOI: 10.1038/ncomms4985</identifier><identifier>PMID: 24905191</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>45 ; 631/158/855 ; 631/326/417 ; 692/699/255/1629 ; Animal biology ; Animals ; Anopheles ; Anopheles - microbiology ; Burkina Faso ; Ecology, environment ; Female ; Gram-Negative Bacterial Infections ; Gram-Negative Bacterial Infections - microbiology ; Gram-Negative Bacterial Infections - transmission ; Humanities and Social Sciences ; Life Sciences ; Male ; Mosquito Control ; multidisciplinary ; Phylogeny ; RNA, Ribosomal, 16S ; RNA, Ribosomal, 16S - genetics ; Science ; Science (multidisciplinary) ; Symbiosis ; Veterinary medicine and animal Health ; Wolbachia ; Wolbachia - genetics ; Wolbachia - isolation &amp; purification</subject><ispartof>Nature communications, 2014-06, Vol.5 (1), p.3985, Article 3985</ispartof><rights>The Author(s) 2014</rights><rights>Copyright Nature Publishing Group Jun 2014</rights><rights>Attribution - NonCommercial - NoDerivatives</rights><rights>Copyright © 2014, Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved. 2014 Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c542t-854b7e7a93fff93a5beb7e825e74e56fbfc3e2d5c3182bceba44b72bbfc0e71d3</citedby><cites>FETCH-LOGICAL-c542t-854b7e7a93fff93a5beb7e825e74e56fbfc3e2d5c3182bceba44b72bbfc0e71d3</cites><orcidid>0000-0003-3295-6683 ; 0000-0002-9666-9395 ; 0000-0002-1583-5794</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/1532970968/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/1532970968?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,37013,44590,53791,53793,75126</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24905191$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://hal.science/hal-03280618$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Baldini, Francesco</creatorcontrib><creatorcontrib>Segata, Nicola</creatorcontrib><creatorcontrib>Pompon, Julien</creatorcontrib><creatorcontrib>Marcenac, Perrine</creatorcontrib><creatorcontrib>Robert Shaw, W.</creatorcontrib><creatorcontrib>Dabiré, Roch K.</creatorcontrib><creatorcontrib>Diabaté, Abdoulaye</creatorcontrib><creatorcontrib>Levashina, Elena A.</creatorcontrib><creatorcontrib>Catteruccia, Flaminia</creatorcontrib><title>Evidence of natural Wolbachia infections in field populations of Anopheles gambiae</title><title>Nature communications</title><addtitle>Nat Commun</addtitle><addtitle>Nat Commun</addtitle><description>Wolbachia are maternally transmitted intracellular bacteria that invade insect populations by manipulating their reproduction and immunity and thus limiting the spread of numerous human pathogens. Experimental Wolbachia infections can reduce Plasmodium numbers in Anopheles mosquitoes in the laboratory, however, natural Wolbachia infections in field anophelines have never been reported. Here we show evidence of Wolbachia infections in Anopheles gambiae in Burkina Faso, West Africa. Sequencing of the 16S rRNA gene identified Wolbachia sequences in both female and male germlines across two seasons, and determined that these sequences are vertically transmitted from mother to offspring. Whole-genome sequencing of positive samples suggests that the genetic material identified in An. gambiae belongs to a novel Wolbachia strain, related to but distinct from strains infecting other arthropods. The evidence of Wolbachia infections in natural Anopheles populations promotes further investigations on the possible use of natural Wolbachia – Anopheles associations to limit malaria transmission. Wolbachia bacteria live within the cells of many insect species, manipulating their hosts’ reproduction and immune responses. Here, the authors show that these microbes also infect wild populations of malaria-spreading Anopheles mosquitoes, supporting a potential use of Wolbachia to limit malaria transmission.</description><subject>45</subject><subject>631/158/855</subject><subject>631/326/417</subject><subject>692/699/255/1629</subject><subject>Animal biology</subject><subject>Animals</subject><subject>Anopheles</subject><subject>Anopheles - microbiology</subject><subject>Burkina Faso</subject><subject>Ecology, environment</subject><subject>Female</subject><subject>Gram-Negative Bacterial Infections</subject><subject>Gram-Negative Bacterial Infections - microbiology</subject><subject>Gram-Negative Bacterial Infections - transmission</subject><subject>Humanities and Social Sciences</subject><subject>Life Sciences</subject><subject>Male</subject><subject>Mosquito Control</subject><subject>multidisciplinary</subject><subject>Phylogeny</subject><subject>RNA, Ribosomal, 16S</subject><subject>RNA, Ribosomal, 16S - genetics</subject><subject>Science</subject><subject>Science (multidisciplinary)</subject><subject>Symbiosis</subject><subject>Veterinary medicine and animal Health</subject><subject>Wolbachia</subject><subject>Wolbachia - genetics</subject><subject>Wolbachia - isolation &amp; purification</subject><issn>2041-1723</issn><issn>2041-1723</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><recordid>eNplkd9rFDEQx4NYbDn74h8gC75o5TQ_b5MX4SitFQ4EUXwMSXZyl7KbrJvdA_97c2xtr21eMpn5zHcmMwi9IfgTwUx-ji51XeZKihfojGJOlqSm7OWRfYrOc77F5TBFJOev0CnlCguiyBn6cbUPDUQHVfJVNOM0mLb6nVpr3C6YKkQPbgwp5mJWPkDbVH3qp9bMzpK0jqnfQQu52prOBgOv0Yk3bYbzu3uBfl1f_by8WW6-f_12ud4sneB0XErBbQ21Ucx7r5gRFspbUgE1B7Hy1jsGtBGOEUmtA2t4SaC2-DHUpGEL9GXW7SfbQeMgjqV53Q-hM8NfnUzQjyMx7PQ27TXHQinKi8CHWWD3JO1mvdEHH2ZU4hWRe1LY93fFhvRngjzqLmQHbWsipClrIhjnNSdlyAv07gl6m6YhllEcKKpqrFayUBcz5YaU8wD-vgOC9WGz-mGzBX57_NV79P8eC_BxBnIJxS0MRzWfy_0DCbKvhA</recordid><startdate>20140606</startdate><enddate>20140606</enddate><creator>Baldini, Francesco</creator><creator>Segata, Nicola</creator><creator>Pompon, Julien</creator><creator>Marcenac, Perrine</creator><creator>Robert Shaw, W.</creator><creator>Dabiré, Roch K.</creator><creator>Diabaté, Abdoulaye</creator><creator>Levashina, Elena A.</creator><creator>Catteruccia, Flaminia</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><general>Nature Pub. Group</general><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7QP</scope><scope>7QR</scope><scope>7SN</scope><scope>7SS</scope><scope>7ST</scope><scope>7T5</scope><scope>7T7</scope><scope>7TM</scope><scope>7TO</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>RC3</scope><scope>SOI</scope><scope>7X8</scope><scope>1XC</scope><scope>VOOES</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-3295-6683</orcidid><orcidid>https://orcid.org/0000-0002-9666-9395</orcidid><orcidid>https://orcid.org/0000-0002-1583-5794</orcidid></search><sort><creationdate>20140606</creationdate><title>Evidence of natural Wolbachia infections in field populations of Anopheles gambiae</title><author>Baldini, Francesco ; Segata, Nicola ; Pompon, Julien ; Marcenac, Perrine ; Robert Shaw, W. ; Dabiré, Roch K. ; Diabaté, Abdoulaye ; Levashina, Elena A. ; Catteruccia, Flaminia</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c542t-854b7e7a93fff93a5beb7e825e74e56fbfc3e2d5c3182bceba44b72bbfc0e71d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>45</topic><topic>631/158/855</topic><topic>631/326/417</topic><topic>692/699/255/1629</topic><topic>Animal biology</topic><topic>Animals</topic><topic>Anopheles</topic><topic>Anopheles - microbiology</topic><topic>Burkina Faso</topic><topic>Ecology, environment</topic><topic>Female</topic><topic>Gram-Negative Bacterial Infections</topic><topic>Gram-Negative Bacterial Infections - microbiology</topic><topic>Gram-Negative Bacterial Infections - transmission</topic><topic>Humanities and Social Sciences</topic><topic>Life Sciences</topic><topic>Male</topic><topic>Mosquito Control</topic><topic>multidisciplinary</topic><topic>Phylogeny</topic><topic>RNA, Ribosomal, 16S</topic><topic>RNA, Ribosomal, 16S - genetics</topic><topic>Science</topic><topic>Science (multidisciplinary)</topic><topic>Symbiosis</topic><topic>Veterinary medicine and animal Health</topic><topic>Wolbachia</topic><topic>Wolbachia - genetics</topic><topic>Wolbachia - isolation &amp; purification</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Baldini, Francesco</creatorcontrib><creatorcontrib>Segata, Nicola</creatorcontrib><creatorcontrib>Pompon, Julien</creatorcontrib><creatorcontrib>Marcenac, Perrine</creatorcontrib><creatorcontrib>Robert Shaw, W.</creatorcontrib><creatorcontrib>Dabiré, Roch K.</creatorcontrib><creatorcontrib>Diabaté, Abdoulaye</creatorcontrib><creatorcontrib>Levashina, Elena A.</creatorcontrib><creatorcontrib>Catteruccia, Flaminia</creatorcontrib><collection>SpringerOpen</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Calcium &amp; Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Environment Abstracts</collection><collection>Immunology Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Nucleic Acids Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Proquest Health &amp; Medical Complete</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>Advanced Technologies &amp; Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Biological Sciences</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Advanced Technologies &amp; Aerospace Database</collection><collection>ProQuest Advanced Technologies &amp; Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Genetics Abstracts</collection><collection>Environment Abstracts</collection><collection>MEDLINE - Academic</collection><collection>Hyper Article en Ligne (HAL)</collection><collection>Hyper Article en Ligne (HAL) (Open Access)</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Nature communications</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Baldini, Francesco</au><au>Segata, Nicola</au><au>Pompon, Julien</au><au>Marcenac, Perrine</au><au>Robert Shaw, W.</au><au>Dabiré, Roch K.</au><au>Diabaté, Abdoulaye</au><au>Levashina, Elena A.</au><au>Catteruccia, Flaminia</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evidence of natural Wolbachia infections in field populations of Anopheles gambiae</atitle><jtitle>Nature communications</jtitle><stitle>Nat Commun</stitle><addtitle>Nat Commun</addtitle><date>2014-06-06</date><risdate>2014</risdate><volume>5</volume><issue>1</issue><spage>3985</spage><pages>3985-</pages><artnum>3985</artnum><issn>2041-1723</issn><eissn>2041-1723</eissn><abstract>Wolbachia are maternally transmitted intracellular bacteria that invade insect populations by manipulating their reproduction and immunity and thus limiting the spread of numerous human pathogens. Experimental Wolbachia infections can reduce Plasmodium numbers in Anopheles mosquitoes in the laboratory, however, natural Wolbachia infections in field anophelines have never been reported. Here we show evidence of Wolbachia infections in Anopheles gambiae in Burkina Faso, West Africa. Sequencing of the 16S rRNA gene identified Wolbachia sequences in both female and male germlines across two seasons, and determined that these sequences are vertically transmitted from mother to offspring. Whole-genome sequencing of positive samples suggests that the genetic material identified in An. gambiae belongs to a novel Wolbachia strain, related to but distinct from strains infecting other arthropods. The evidence of Wolbachia infections in natural Anopheles populations promotes further investigations on the possible use of natural Wolbachia – Anopheles associations to limit malaria transmission. Wolbachia bacteria live within the cells of many insect species, manipulating their hosts’ reproduction and immune responses. Here, the authors show that these microbes also infect wild populations of malaria-spreading Anopheles mosquitoes, supporting a potential use of Wolbachia to limit malaria transmission.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>24905191</pmid><doi>10.1038/ncomms4985</doi><orcidid>https://orcid.org/0000-0003-3295-6683</orcidid><orcidid>https://orcid.org/0000-0002-9666-9395</orcidid><orcidid>https://orcid.org/0000-0002-1583-5794</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2041-1723
ispartof Nature communications, 2014-06, Vol.5 (1), p.3985, Article 3985
issn 2041-1723
2041-1723
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4059924
source Publicly Available Content Database; Nature; PubMed Central; Springer Nature - nature.com Journals - Fully Open Access
subjects 45
631/158/855
631/326/417
692/699/255/1629
Animal biology
Animals
Anopheles
Anopheles - microbiology
Burkina Faso
Ecology, environment
Female
Gram-Negative Bacterial Infections
Gram-Negative Bacterial Infections - microbiology
Gram-Negative Bacterial Infections - transmission
Humanities and Social Sciences
Life Sciences
Male
Mosquito Control
multidisciplinary
Phylogeny
RNA, Ribosomal, 16S
RNA, Ribosomal, 16S - genetics
Science
Science (multidisciplinary)
Symbiosis
Veterinary medicine and animal Health
Wolbachia
Wolbachia - genetics
Wolbachia - isolation & purification
title Evidence of natural Wolbachia infections in field populations of Anopheles gambiae
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-05T22%3A10%3A07IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Evidence%20of%20natural%20Wolbachia%20infections%20in%20field%20populations%20of%20Anopheles%20gambiae&rft.jtitle=Nature%20communications&rft.au=Baldini,%20Francesco&rft.date=2014-06-06&rft.volume=5&rft.issue=1&rft.spage=3985&rft.pages=3985-&rft.artnum=3985&rft.issn=2041-1723&rft.eissn=2041-1723&rft_id=info:doi/10.1038/ncomms4985&rft_dat=%3Cproquest_pubme%3E3326449131%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c542t-854b7e7a93fff93a5beb7e825e74e56fbfc3e2d5c3182bceba44b72bbfc0e71d3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1532970968&rft_id=info:pmid/24905191&rfr_iscdi=true