Oncological and Functional Outcome after Surgical Treatment of Early Glottic Carcinoma without Anterior Commissure Involvement

Introduction. Glottic carcinoma can be successfully diagnosed in its early stages and treated with high percentage of success. Organ preservation and optimal functional outcomes could be achieved with wide array of surgical techniques for early glottic cancer, including endoscopic approaches or open...

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Published in:BioMed research international 2014-01, Vol.2014 (2014), p.1-7
Main Authors: Milovanovic, Jovica, Jotic, Ana, Djukic, Vojko, Pavlovic, Bojan, Trivic, Aleksandar, Krejovic-Trivic, Sanja, Milovanovic, Andjela, Milovanovic, Aleksandar, Artiko, Vera, Banko, Bojan
Format: Article
Language:English
Subjects:
Aged
Biomedical research
Carcinoma, Squamous Cell - pathology
Carcinoma, Squamous Cell - surgery
Endoscopy
Female
Humans
Laryngeal cancer
Laryngeal Neoplasms - pathology
Laryngeal Neoplasms - surgery
Laser Therapy
Lasers
Male
Maxillofacial surgery
Medical treatment
Middle Aged
Neoplasm Staging
Otolaryngology
Prospective Studies
Radiation therapy
Surgery
Symmetry
Treatment Outcome
Vocal Cords - pathology
Vocal Cords - surgery
Voice - physiology
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Summary:Introduction. Glottic carcinoma can be successfully diagnosed in its early stages and treated with high percentage of success. Organ preservation and optimal functional outcomes could be achieved with wide array of surgical techniques for early glottic cancer, including endoscopic approaches or open laryngeal preserving procedures, making surgery the preferred method of treatment of early glottic carcinoma in the last few years. Material and Methods. Prospective study was done on 59 patients treated for Tis and T1a glottic carcinoma over a one-year time period in a tertiary medical center. Patients were treated with endoscopic laser cordectomy (types II–IV cordectomies according to European Laryngological Society classification of endoscopic cordectomies) and open cordectomy through laryngofissure. Follow-up period was 60 months. Clinical and oncological results were followed postoperatively. Voice quality after the treatment was assessed using multidimensional voice analysis 12 months after the treatment. Results. There were no significant differences between oncological and functional results among two groups of patients, though complications were more frequent in patients treated with open cordectomy. Conclusion. Endoscopic laser surgery should be the first treatment of choice in treatment of early glottic carcinomas, though open approach through laryngofissure should be available for selected cases where anatomical factors present limiting adequate tumor removal.
ISSN:2314-6133
2314-6141
DOI:10.1155/2014/464781