Effects of Electroacupuncture on Facial Nerve Function and HSV-1 DNA Quantity in HSV-1 Induced Facial Nerve Palsy Mice

Acupuncture is a common and effective therapeutic method to treat facial nerve palsy (FNP). However, its underlying mechanism remains unclear. This study was aimed to investigate the effects of electroacupuncture on symptoms and content of HSV-1 DNA in FNP mice. Mice were randomized into four groups...

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Bibliographic Details
Published in:Evidence-based complementary and alternative medicine 2014-01, Vol.2014 (2014), p.1-7
Main Authors: Liang, Fan-Rong, Zhong, Zhendong, Yang, Ming-Xiao, Yang, Jie, Chen, Jiao, Feng, Shu-Wei, Tang, Hongzhi, Li, Ying
Format: Article
Language:English
Subjects:
Acupuncture
Chinese medicine
Deoxyribonucleic acid
DNA
Electroacupuncture
Facial nerve
Herpes simplex virus 1
Mice
Paralysis
Rodents
Viral infections
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Summary:Acupuncture is a common and effective therapeutic method to treat facial nerve palsy (FNP). However, its underlying mechanism remains unclear. This study was aimed to investigate the effects of electroacupuncture on symptoms and content of HSV-1 DNA in FNP mice. Mice were randomized into four groups, an electroacupuncture treatment group, saline group, model animal group, and blank control group. Electroacupuncture was applied at Jiache (ST6) and Hegu (LI4) in electroacupuncture group once daily for 14 days, while electroacupuncture was not applied in model animal group. In electroacupuncture group, mice recovered more rapidly and HSV-1 DNA content also decreased more rapidly, compared with model animal group. We conclude that electroacupuncture is effective to alleviate symptoms and promote the reduction of HSV-1 in FNP.
ISSN:1741-427X
1741-4288
DOI:10.1155/2014/693783