Risk of leukemia in relation to exposure to ambient air toxics in pregnancy and early childhood

There are few established causes of leukemia, the most common type of cancer in children. Studies in adults suggest a role for specific environmental agents, but little is known about any effect from exposures in pregnancy to toxics in ambient air. In our case–control study, we ascertained 69 cases...

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Bibliographic Details
Published in:International journal of hygiene and environmental health 2014-07, Vol.217 (6), p.662-668
Main Authors: Heck, Julia E., Park, Andrew S., Qiu, Jiaheng, Cockburn, Myles, Ritz, Beate
Format: Article
Language:English
Subjects:
Air
Air Pollutants - adverse effects
Arsenic
Arsenic - adverse effects
Benzene
Biological and medical sciences
Butadienes - adverse effects
California
Case-Control Studies
Child, Preschool
Childhood cancer epidemiology
Childhood leukemia
Chloroform
Chloroform - adverse effects
Environmental Exposure - adverse effects
Environmental pollutants toxicology
Female
Humans
Hydrocarbons, Cyclic - adverse effects
Infant
Lead
Leukemia, Myeloid, Acute - etiology
Logistic Models
Maternal Exposure - adverse effects
Medical sciences
Polycyclic aromatic hydrocarbons
Precursor Cell Lymphoblastic Leukemia-Lymphoma - etiology
Pregnancy
Risk Factors
Selenium - adverse effects
Toluene
Toxicology
Vehicle Emissions - toxicity
Xylenes
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Summary:There are few established causes of leukemia, the most common type of cancer in children. Studies in adults suggest a role for specific environmental agents, but little is known about any effect from exposures in pregnancy to toxics in ambient air. In our case–control study, we ascertained 69 cases of acute lymphoblastic leukemia (ALL) and 46 cases of acute myeloid leukemia (AML) from California Cancer Registry records of children
ISSN:1438-4639
1618-131X
DOI:10.1016/j.ijheh.2013.12.003