Effect of PDGF, IGF-1 and PRP on the implant osseointegration. An histological and immunohistochemical study in rabbits

The ability of platelet-derived growth factor (PDGF), insulin-like growth factor-1 (IGF-1) and platelet-rich plasma (PRP) to increase the rate of osseointegration of endosseous implants and to improve the quality of bone remodeling on the surface of titanium, has been investigated in an experimental...

Full description

Saved in:
Bibliographic Details
Published in:Annali di stomatologia 2014-04, Vol.5 (2), p.66-68
Main Authors: Ortolani, Emanuela, Guerriero, Massimiliano, Coli, Antonella, Di Giannuario, Amalia, Minniti, Gianluca, Polimeni, Antonella
Format: Article
Language:English
Subjects:
Animals
Blood platelets
Cell growth
Histology
Insulin-like growth factors
Original
Surgery
Vascular endothelial growth factor
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The ability of platelet-derived growth factor (PDGF), insulin-like growth factor-1 (IGF-1) and platelet-rich plasma (PRP) to increase the rate of osseointegration of endosseous implants and to improve the quality of bone remodeling on the surface of titanium, has been investigated in an experimental intraosseous defect model by an histological and immunohistochemical evaluation. The results from this study demonstrate that rabbits treated with the combination PDGF/IGF-1 showed a higher positive effect on bone regeneration than PRP-treated or controls.
ISSN:1824-0852
1971-1441
1971-1441
DOI:10.11138/ads/2014.5.2.066