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Primary malignant melanoma of uterine cervix: a suggestion of new scheme of treatment combination
Historically, the lack of melanocytes in the vaginal and cervical mucus membranes has deterred the findings of primary melanomas. Mainly due to its rarity, difficulty to diagnose, and poor prognosis, there has been no absolute agreement on comprehensive treatment so far. In this case report, we pres...
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Published in: | Chinese journal of cancer research 2014-06, Vol.26 (3), p.351-354 |
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container_end_page | 354 |
container_issue | 3 |
container_start_page | 351 |
container_title | Chinese journal of cancer research |
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creator | Min, Kyung-Jin Kim, Yeun-Sun Hong, Jin-Hwa Lee, Jae-Kwan Yang, Dae-Sik |
description | Historically, the lack of melanocytes in the vaginal and cervical mucus membranes has deterred the findings of primary melanomas. Mainly due to its rarity, difficulty to diagnose, and poor prognosis, there has been no absolute agreement on comprehensive treatment so far. In this case report, we present a case of a 46-year-old woman with primary malignant melanoma of uterine cervix. She underwent neo-adjuvant chemotherapy initially followed by a radical hysterectomy. After adjuvant concurrent chemo-radiation, the patient has been followed up for 24 months. So far, she has not shown any symptoms or signs of recurrence. Further studies with more cases based on variable combinations of treatment regimen have been on the way. |
doi_str_mv | 10.3978/j.issn.1000-9604.2014.06.03 |
format | article |
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Mainly due to its rarity, difficulty to diagnose, and poor prognosis, there has been no absolute agreement on comprehensive treatment so far. In this case report, we present a case of a 46-year-old woman with primary malignant melanoma of uterine cervix. She underwent neo-adjuvant chemotherapy initially followed by a radical hysterectomy. After adjuvant concurrent chemo-radiation, the patient has been followed up for 24 months. So far, she has not shown any symptoms or signs of recurrence. Further studies with more cases based on variable combinations of treatment regimen have been on the way.</description><identifier>ISSN: 1000-9604</identifier><identifier>EISSN: 1993-0631</identifier><identifier>DOI: 10.3978/j.issn.1000-9604.2014.06.03</identifier><identifier>PMID: 25035664</identifier><language>eng</language><publisher>China: Department of Obstetrics and Gynaecology, Korea University Medical Centre, Seoul 152-703, South Korea%Department of Radiation Oncology, Korea University Medical Centre, Seoul 152-703, South Korea</publisher><subject>Case Report ; 原发性 ; 同步辐射 ; 子宫切除 ; 宫颈 ; 恶性黑色素瘤 ; 综合治疗 ; 调查结果 ; 黑色素细胞</subject><ispartof>Chinese journal of cancer research, 2014-06, Vol.26 (3), p.351-354</ispartof><rights>Copyright © Wanfang Data Co. Ltd. All Rights Reserved.</rights><rights>2014 Chinese Journal of Cancer Research. 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Further studies with more cases based on variable combinations of treatment regimen have been on the way.</description><subject>Case Report</subject><subject>原发性</subject><subject>同步辐射</subject><subject>子宫切除</subject><subject>宫颈</subject><subject>恶性黑色素瘤</subject><subject>综合治疗</subject><subject>调查结果</subject><subject>黑色素细胞</subject><issn>1000-9604</issn><issn>1993-0631</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><recordid>eNpVkEtOxDAMhiME4n0FVMGCVYtTT5N2g4RGvCQkWMC6clO3k9E0hbbD6yichTtxBTIaBsHKsfLp828LcSQhwkynJ9PI9r2LJACEmYJRFIMcRaAiwDWxLbMMQ1Ao1_17hWyJnb6fAiQ6AbkptuIEMFFqtC3MXWcb6t6Chma2duSGoOEZubahoK2C-cCddRwY7p7t69fnR0BBP69r7gfbugXh-CXozYQbXnRDxzQ07C2mbQrraIHtiY2KZj3v_9Rd8XBxfj--Cm9uL6_HZzehwQSGUJaYpgWCiikzxJUsqirTJcjKSKnLxGcuU-YCsUqBCZMMYyUR45KIARl3xenS-zgvGi6Nj9HRLH9cbpi3ZPP_P85O8rp9zkeglZaJFxwvBS_kKnJ1Pm3nnfOR8_ea3t-mi0MDQhx78uDvqN8Zq8N64HAJmEnr6ifrZStGKZlqDTrGb5BwjRg</recordid><startdate>20140601</startdate><enddate>20140601</enddate><creator>Min, Kyung-Jin</creator><creator>Kim, Yeun-Sun</creator><creator>Hong, Jin-Hwa</creator><creator>Lee, Jae-Kwan</creator><creator>Yang, Dae-Sik</creator><general>Department of Obstetrics and Gynaecology, Korea University Medical Centre, Seoul 152-703, South Korea%Department of Radiation Oncology, Korea University Medical Centre, Seoul 152-703, South Korea</general><general>AME Publishing Company</general><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>W91</scope><scope>~WA</scope><scope>NPM</scope><scope>2B.</scope><scope>4A8</scope><scope>92I</scope><scope>93N</scope><scope>PSX</scope><scope>TCJ</scope><scope>5PM</scope></search><sort><creationdate>20140601</creationdate><title>Primary malignant melanoma of uterine cervix: a suggestion of new scheme of treatment combination</title><author>Min, Kyung-Jin ; Kim, Yeun-Sun ; Hong, Jin-Hwa ; Lee, Jae-Kwan ; Yang, Dae-Sik</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c350t-1d388b3062a9caef1bff97d01fc117d5503d8eeb33f80ea3593261332daae03e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Case Report</topic><topic>原发性</topic><topic>同步辐射</topic><topic>子宫切除</topic><topic>宫颈</topic><topic>恶性黑色素瘤</topic><topic>综合治疗</topic><topic>调查结果</topic><topic>黑色素细胞</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Min, Kyung-Jin</creatorcontrib><creatorcontrib>Kim, Yeun-Sun</creatorcontrib><creatorcontrib>Hong, Jin-Hwa</creatorcontrib><creatorcontrib>Lee, Jae-Kwan</creatorcontrib><creatorcontrib>Yang, Dae-Sik</creatorcontrib><collection>维普_期刊</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>维普中文期刊数据库</collection><collection>维普中文医药期刊数据库</collection><collection>中文科技期刊数据库- 镜像站点</collection><collection>PubMed</collection><collection>Wanfang Data Journals - Hong Kong</collection><collection>WANFANG Data Centre</collection><collection>Wanfang Data Journals</collection><collection>万方数据期刊 - 香港版</collection><collection>China Online Journals (COJ)</collection><collection>China Online Journals (COJ)</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Chinese journal of cancer research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Min, Kyung-Jin</au><au>Kim, Yeun-Sun</au><au>Hong, Jin-Hwa</au><au>Lee, Jae-Kwan</au><au>Yang, Dae-Sik</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Primary malignant melanoma of uterine cervix: a suggestion of new scheme of treatment combination</atitle><jtitle>Chinese journal of cancer research</jtitle><addtitle>Chinese Journal of Cancer Research</addtitle><date>2014-06-01</date><risdate>2014</risdate><volume>26</volume><issue>3</issue><spage>351</spage><epage>354</epage><pages>351-354</pages><issn>1000-9604</issn><eissn>1993-0631</eissn><abstract>Historically, the lack of melanocytes in the vaginal and cervical mucus membranes has deterred the findings of primary melanomas. Mainly due to its rarity, difficulty to diagnose, and poor prognosis, there has been no absolute agreement on comprehensive treatment so far. In this case report, we present a case of a 46-year-old woman with primary malignant melanoma of uterine cervix. She underwent neo-adjuvant chemotherapy initially followed by a radical hysterectomy. After adjuvant concurrent chemo-radiation, the patient has been followed up for 24 months. So far, she has not shown any symptoms or signs of recurrence. Further studies with more cases based on variable combinations of treatment regimen have been on the way.</abstract><cop>China</cop><pub>Department of Obstetrics and Gynaecology, Korea University Medical Centre, Seoul 152-703, South Korea%Department of Radiation Oncology, Korea University Medical Centre, Seoul 152-703, South Korea</pub><pmid>25035664</pmid><doi>10.3978/j.issn.1000-9604.2014.06.03</doi><tpages>4</tpages></addata></record> |
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ispartof | Chinese journal of cancer research, 2014-06, Vol.26 (3), p.351-354 |
issn | 1000-9604 1993-0631 |
language | eng |
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source | PubMed (Medline) |
subjects | Case Report 原发性 同步辐射 子宫切除 宫颈 恶性黑色素瘤 综合治疗 调查结果 黑色素细胞 |
title | Primary malignant melanoma of uterine cervix: a suggestion of new scheme of treatment combination |
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