Laparoscopic resection for hepatocellular carcinoma： eastern and western experiences

• Published in: Chinese journal of cancer research 2014-06, Vol.26 (3), p.234-236
• Main Authors: Herman, Paulo, Coelho, Fabricio Ferreira
• Format: Article
• Language: English
• Subjects: 丙型肝炎; 东方; 原发性肝癌; 筛选程序; 肝细胞癌; 腹腔镜; 致病因素; 西方国家
• ISSN: 1000-9604; 1993-0631
• DOI: 10.3978/j.issn.1000-9604.2014.06.19

Hepatocellular carcinoma （HCC） is the most common primary liver cancer （1）. The incidence is rising in the last decades due to many factors, especially hepatitis C, alcoholic liver disease and non-alcoholic steatohepatitis. Moreover, the introduction of screening programs in patients with chronic liver disease has led to an increase in HCC diagnosis （1,2）. In the western world, 80% to 90% of HCC eases occur in patients with liver cirrhosis （3） while this proportion is lower in some regions in Asia and sub-Saharian Africa, where hepatitis B remains as an important etiologic factor for chronic liver disease （2,4）. In 1990, the annual world frequency of HCC was 437,000 cases/year （1）, and in 2012 the number reached 782,200 cases/year being responsible for 746,000 deaths （5）. Nowadays, HCC represents the 6th most frequent neoplastic disease in the world and the 3rd in mortality （5）.