Treatment of hyperbilirubinemia with blood purification in China

The incidence of hyperbilirubinemia is high clinically, which is difficult to cure by medication, surgery or interventional therapies. Non-bioartificial liver is the main alternative in the blood purification for hyperbilirubinemia, which includes plasma exchange, hemoperfusion, hemodialysis, molecu...

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Bibliographic Details
Published in:World journal of gastroenterology : WJG 2006-12, Vol.12 (46), p.7467-7471
Main Authors: Duan, Zhi-Jun, Li, Lei-Lei, Ju, Jia, Gao, Zhi-Hong, He, Gao-Hong
Format: Article
Language:English
Subjects:
Bilirubin - blood
Bilirubin - isolation & purification
China
Hemoperfusion
Humans
Hyperbilirubinemia - blood
Hyperbilirubinemia - therapy
Liver, Artificial
Plasma Exchange
Renal Dialysis
Review
Sorption Detoxification - methods
人工肝
血液净化
高胆红素血症
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Summary:The incidence of hyperbilirubinemia is high clinically, which is difficult to cure by medication, surgery or interventional therapies. Non-bioartificial liver is the main alternative in the blood purification for hyperbilirubinemia, which includes plasma exchange, hemoperfusion, hemodialysis, molecular adsorbent recycling system and so on. The research results and clinical experiences in China show that these methods are effective in lowering high levels of bilirubin with fewer side effects. The hyperbilirubinemias of different causes, with different complications or accompanying different diseases can be treated by different methods. Bioartificial liver, hybrid artificial liver support system and adsorbent membrane material have also been studied and their development in reducing hyperbilirubinemias has been achieved. This article gives a brief overview on the actuality and research improvement in blood purification for hyperbilirubinemia in China.
ISSN:1007-9327
2219-2840
DOI:10.3748/wjg.v12.i46.7467