Intestinal mucosal adaptation

Intestinal failure is a condition characterized by malnutrition and/or dehydration as a result of the inadequate digestion and absorption of nutrients. The most common cause of intestinal failure is short bowel syndrome, which occurs when the functional gut mass is reduced below the level necessary...

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Bibliographic Details
Published in:World journal of gastroenterology : WJG 2006-08, Vol.12 (29), p.4614-4627
Main Authors: Drozdowski, Laurie, Thomson, Alan B R
Format: Article
Language:English
Subjects:
Adaptation, Physiological - physiology
Animals
Disease Models, Animal
Feeding Behavior - physiology
Gastrointestinal Hormones - physiology
Humans
Intestinal Mucosa - metabolism
Intestinal Mucosa - physiopathology
Rats
Review
Short Bowel Syndrome - metabolism
Short Bowel Syndrome - physiopathology
Short Bowel Syndrome - surgery
Signal Transduction - physiology
Swine
形态学
肠吸收
肠道运输
黏膜疾病
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Summary:Intestinal failure is a condition characterized by malnutrition and/or dehydration as a result of the inadequate digestion and absorption of nutrients. The most common cause of intestinal failure is short bowel syndrome, which occurs when the functional gut mass is reduced below the level necessary for adequate nutrient and water absorption. This condition may be congenital, or may be acquired as a result of a massive resection of the small bowel. Following resection, the intestine is capable of adaptation in response to enteral nutrients as well as other trophic stimuli. Identifying factors that may enhance the process of intestinal adaptation is an exciting area of research with important potential clinical applications.
ISSN:1007-9327
2219-2840
DOI:10.3748/wjg.v12.i29.4614