Urinary kidney injury molecule-1 is related to pathologic involvement in IgA nephropathy with normotension, normal renal function and mild proteinuria

IgA nephropathy (IgAN) may progress to renal failure for some patients without any clinical risk factors and it is not unusual to find severe pathologic damage in clinically mild IgAN. We therefore investigated whether urinary kidney injury molecule-1 (KIM-1) was related to pathologic involvement in...

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Bibliographic Details
Published in:BMC nephrology 2014-07, Vol.15 (1), p.107-107, Article 107
Main Authors: Xu, Peng-cheng, Wei, Li, Shang, Wen-ya, Tian, Shun-li, Gu, Dong-mei, Yan, Tie-kun, Lin, Shan
Format: Article
Language:English
Subjects:
Adult
Biomarkers
Biomarkers - urine
Biopsy
Classification
Female
Follow-Up Studies
Glomerulonephritis, IGA - diagnosis
Glomerulonephritis, IGA - epidemiology
Glomerulonephritis, IGA - urine
Hepatitis A Virus Cellular Receptor 1
Humans
Kidney - physiology
Kidney diseases
Male
Medical prognosis
Medical treatment
Membrane Glycoproteins - urine
Nephrology
Proteinuria - diagnosis
Proteinuria - epidemiology
Proteinuria - urine
Receptors, Virus
Risk factors
Rodents
Studies
Urine
Young Adult
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Summary:IgA nephropathy (IgAN) may progress to renal failure for some patients without any clinical risk factors and it is not unusual to find severe pathologic damage in clinically mild IgAN. We therefore investigated whether urinary kidney injury molecule-1 (KIM-1) was related to pathologic involvement in clinically mild IgAN. Urinary KIM-1/creatinine of 51 IgAN patients with normotension, normal renal function and proteinuria 
ISSN:1471-2369
1471-2369
DOI:10.1186/1471-2369-15-107