Travelling within the fetal gut: simple rules for an arduous journey

The complex physiology of the gastrointestinal tract is regulated by intricate neural networks embedded within the gut wall. How neural crest cells colonize the intestine to form the enteric nervous system is of great interest to developmental biologists, but also highly relevant for understanding g...

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Bibliographic Details
Published in:BMC biology 2014-06, Vol.12 (1), p.50-50, Article 50
Main Authors: Xu, Qiling, Heanue, Tiffany, Pachnis, Vassilis
Format: Article
Language:English
Subjects:
Analysis
Animal behavior
Animals
Cell Movement
Enteric Nervous System - cytology
Gastrointestinal diseases
Neural Crest - cytology
Neurons
Physiological aspects
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Summary:The complex physiology of the gastrointestinal tract is regulated by intricate neural networks embedded within the gut wall. How neural crest cells colonize the intestine to form the enteric nervous system is of great interest to developmental biologists, but also highly relevant for understanding gastrointestinal disorders. A recent paper in BMC Biology addresses this issue with live imaging of gut explants from mouse embryos.
ISSN:1741-7007
1741-7007
DOI:10.1186/s12915-014-0050-z