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Cardiopulmonary exercise testing as a predictor of complications in oesophagogastric cancer surgery
An anaerobic threshold (AT) of
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| Published in: | Annals of the Royal College of Surgeons of England 2013-03, Vol.95 (2), p.125-130 |
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| container_issue | 2 |
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| container_title | Annals of the Royal College of Surgeons of England |
| container_volume | 95 |
| creator | Moyes, L H McCaffer, C J Carter, R C Fullarton, G M Mackay, C K Forshaw, M J |
| description | An anaerobic threshold (AT) of |
| doi_str_mv | 10.1308/003588413X13511609954897 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4098578</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1317407625</sourcerecordid><originalsourceid>FETCH-LOGICAL-c1668-571cdbf268183df8882747974600a668026a84b67d18663bc4c18e81630860e53</originalsourceid><addsrcrecordid>eNpVkE9LxDAUxIMo7rr6FSRHL9W8Jk1eL4Is_oMFLwreSppmu5G2qUkr7re3i6vo6R3ezPyYIYQCuwTO8IoxniEK4K_AMwDJ8jwTmKsDMgehMFEM-SGZ72TJpOMzchLjG2OQK4RjMku5QDF55sQsdaic78em9Z0OW2o_bTAuWjrYOLiupjpSTftgK2cGH6hfU-PbvnFGD853kbqOeht9v9G1r3UcgjPU6M7YQOMYahu2p-RorZtoz_Z3QV7ubp-XD8nq6f5xebNKDEiJSabAVOU6lQjIqzUipkqoXAnJmJ4ELJUaRSlVBSglL40wgBZBTotIZjO-INffuf1YtrYythuCboo-uHZqVnjtiv-fzm2K2n8UguWYKZwCLvYBwb-PU_-iddHYptGd9WMsgIMSTMl0xzr_y_qF_CzLvwB2LX5w</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1317407625</pqid></control><display><type>article</type><title>Cardiopulmonary exercise testing as a predictor of complications in oesophagogastric cancer surgery</title><source>PubMed Central</source><creator>Moyes, L H ; McCaffer, C J ; Carter, R C ; Fullarton, G M ; Mackay, C K ; Forshaw, M J</creator><creatorcontrib>Moyes, L H ; McCaffer, C J ; Carter, R C ; Fullarton, G M ; Mackay, C K ; Forshaw, M J</creatorcontrib><description><![CDATA[An anaerobic threshold (AT) of <11 ml/min/kg can identify patients at high risk of cardiopulmonary complications after major surgery. The aim of this study was to assess the value of cardiopulmonary exercise testing (CPET) in predicting cardiopulmonary complications in high risk patients undergoing oesophagogastric cancer resection.
Between March 2008 and October 2010, 108 patients (83 men, 25 women) with a median age of 66 years (range: 38-84 years) underwent CPET before potentially curative resections for oesophagogastric cancers. Measured CPET variables included AT and maximum oxygen uptake at peak exercise (VO2 peak). Outcome measures were length of high dependency unit stay, length of hospital stay, unplanned intensive care unit (ICU) admission, and postoperative morbidity and mortality.
The mean AT and VO2 peak were 10.8 ml/min/kg (standard deviation [SD]: 2.8 ml/min/kg, range: 4.6-19.3 ml/min/kg) and 15.2 ml/min/kg (SD: 5.3 ml/min/kg, range: 5.4-33.3 ml/min/kg) respectively; 57 patients (55%) had an AT of <11 ml/min/kg and 26 (12%) had an AT of <9 ml/min/kg. Postoperative complications occurred in 57 patients (29 cardiopulmonary [28%] and 28 non-cardiopulmonary [27%]). Four patients (4%) died in hospital and 21 (20%) required an unplanned ICU admission. Cardiopulmonary complications occurred in 42% of patients with an AT of <9 ml/min/kg compared with 29% of patients with an AT of ≥9 ml/min/kg but <11 ml/min/kg and 20% of patients with an AT of ≥11 ml/min/kg (p = 0.04). There was a trend that those with an AT of <11 ml/min/kg and a low VO2 peak had a higher rate of unplanned ICU admission.
This study has shown a correlation between AT and the development of cardiopulmonary complications although the discriminatory ability was low.]]></description><identifier>ISSN: 0035-8843</identifier><identifier>EISSN: 1478-7083</identifier><identifier>DOI: 10.1308/003588413X13511609954897</identifier><identifier>PMID: 23484995</identifier><language>eng</language><publisher>England: Royal College of Surgeons</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Critical Care - statistics & numerical data ; Esophageal Neoplasms - surgery ; Exercise Test ; Heart Diseases - diagnosis ; Heart Diseases - etiology ; Humans ; Length of Stay - statistics & numerical data ; Lung Diseases - diagnosis ; Lung Diseases - etiology ; Middle Aged ; Oxygen Consumption - physiology ; Postoperative Complications - diagnosis ; Postoperative Complications - etiology ; Preoperative Care - methods ; ROC Curve ; Stomach Neoplasms - surgery ; Treatment Outcome ; Upper GI</subject><ispartof>Annals of the Royal College of Surgeons of England, 2013-03, Vol.95 (2), p.125-130</ispartof><rights>Copyright © 2013 Royal College of Surgeons 2013</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c1668-571cdbf268183df8882747974600a668026a84b67d18663bc4c18e81630860e53</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098578/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098578/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,724,777,781,882,27905,27906,53772,53774</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23484995$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Moyes, L H</creatorcontrib><creatorcontrib>McCaffer, C J</creatorcontrib><creatorcontrib>Carter, R C</creatorcontrib><creatorcontrib>Fullarton, G M</creatorcontrib><creatorcontrib>Mackay, C K</creatorcontrib><creatorcontrib>Forshaw, M J</creatorcontrib><title>Cardiopulmonary exercise testing as a predictor of complications in oesophagogastric cancer surgery</title><title>Annals of the Royal College of Surgeons of England</title><addtitle>Ann R Coll Surg Engl</addtitle><description><![CDATA[An anaerobic threshold (AT) of <11 ml/min/kg can identify patients at high risk of cardiopulmonary complications after major surgery. The aim of this study was to assess the value of cardiopulmonary exercise testing (CPET) in predicting cardiopulmonary complications in high risk patients undergoing oesophagogastric cancer resection.
Between March 2008 and October 2010, 108 patients (83 men, 25 women) with a median age of 66 years (range: 38-84 years) underwent CPET before potentially curative resections for oesophagogastric cancers. Measured CPET variables included AT and maximum oxygen uptake at peak exercise (VO2 peak). Outcome measures were length of high dependency unit stay, length of hospital stay, unplanned intensive care unit (ICU) admission, and postoperative morbidity and mortality.
The mean AT and VO2 peak were 10.8 ml/min/kg (standard deviation [SD]: 2.8 ml/min/kg, range: 4.6-19.3 ml/min/kg) and 15.2 ml/min/kg (SD: 5.3 ml/min/kg, range: 5.4-33.3 ml/min/kg) respectively; 57 patients (55%) had an AT of <11 ml/min/kg and 26 (12%) had an AT of <9 ml/min/kg. Postoperative complications occurred in 57 patients (29 cardiopulmonary [28%] and 28 non-cardiopulmonary [27%]). Four patients (4%) died in hospital and 21 (20%) required an unplanned ICU admission. Cardiopulmonary complications occurred in 42% of patients with an AT of <9 ml/min/kg compared with 29% of patients with an AT of ≥9 ml/min/kg but <11 ml/min/kg and 20% of patients with an AT of ≥11 ml/min/kg (p = 0.04). There was a trend that those with an AT of <11 ml/min/kg and a low VO2 peak had a higher rate of unplanned ICU admission.
This study has shown a correlation between AT and the development of cardiopulmonary complications although the discriminatory ability was low.]]></description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Critical Care - statistics & numerical data</subject><subject>Esophageal Neoplasms - surgery</subject><subject>Exercise Test</subject><subject>Heart Diseases - diagnosis</subject><subject>Heart Diseases - etiology</subject><subject>Humans</subject><subject>Length of Stay - statistics & numerical data</subject><subject>Lung Diseases - diagnosis</subject><subject>Lung Diseases - etiology</subject><subject>Middle Aged</subject><subject>Oxygen Consumption - physiology</subject><subject>Postoperative Complications - diagnosis</subject><subject>Postoperative Complications - etiology</subject><subject>Preoperative Care - methods</subject><subject>ROC Curve</subject><subject>Stomach Neoplasms - surgery</subject><subject>Treatment Outcome</subject><subject>Upper GI</subject><issn>0035-8843</issn><issn>1478-7083</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><recordid>eNpVkE9LxDAUxIMo7rr6FSRHL9W8Jk1eL4Is_oMFLwreSppmu5G2qUkr7re3i6vo6R3ezPyYIYQCuwTO8IoxniEK4K_AMwDJ8jwTmKsDMgehMFEM-SGZ72TJpOMzchLjG2OQK4RjMku5QDF55sQsdaic78em9Z0OW2o_bTAuWjrYOLiupjpSTftgK2cGH6hfU-PbvnFGD853kbqOeht9v9G1r3UcgjPU6M7YQOMYahu2p-RorZtoz_Z3QV7ubp-XD8nq6f5xebNKDEiJSabAVOU6lQjIqzUipkqoXAnJmJ4ELJUaRSlVBSglL40wgBZBTotIZjO-INffuf1YtrYythuCboo-uHZqVnjtiv-fzm2K2n8UguWYKZwCLvYBwb-PU_-iddHYptGd9WMsgIMSTMl0xzr_y_qF_CzLvwB2LX5w</recordid><startdate>201303</startdate><enddate>201303</enddate><creator>Moyes, L H</creator><creator>McCaffer, C J</creator><creator>Carter, R C</creator><creator>Fullarton, G M</creator><creator>Mackay, C K</creator><creator>Forshaw, M J</creator><general>Royal College of Surgeons</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>201303</creationdate><title>Cardiopulmonary exercise testing as a predictor of complications in oesophagogastric cancer surgery</title><author>Moyes, L H ; McCaffer, C J ; Carter, R C ; Fullarton, G M ; Mackay, C K ; Forshaw, M J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1668-571cdbf268183df8882747974600a668026a84b67d18663bc4c18e81630860e53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Critical Care - statistics & numerical data</topic><topic>Esophageal Neoplasms - surgery</topic><topic>Exercise Test</topic><topic>Heart Diseases - diagnosis</topic><topic>Heart Diseases - etiology</topic><topic>Humans</topic><topic>Length of Stay - statistics & numerical data</topic><topic>Lung Diseases - diagnosis</topic><topic>Lung Diseases - etiology</topic><topic>Middle Aged</topic><topic>Oxygen Consumption - physiology</topic><topic>Postoperative Complications - diagnosis</topic><topic>Postoperative Complications - etiology</topic><topic>Preoperative Care - methods</topic><topic>ROC Curve</topic><topic>Stomach Neoplasms - surgery</topic><topic>Treatment Outcome</topic><topic>Upper GI</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Moyes, L H</creatorcontrib><creatorcontrib>McCaffer, C J</creatorcontrib><creatorcontrib>Carter, R C</creatorcontrib><creatorcontrib>Fullarton, G M</creatorcontrib><creatorcontrib>Mackay, C K</creatorcontrib><creatorcontrib>Forshaw, M J</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Annals of the Royal College of Surgeons of England</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Moyes, L H</au><au>McCaffer, C J</au><au>Carter, R C</au><au>Fullarton, G M</au><au>Mackay, C K</au><au>Forshaw, M J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cardiopulmonary exercise testing as a predictor of complications in oesophagogastric cancer surgery</atitle><jtitle>Annals of the Royal College of Surgeons of England</jtitle><addtitle>Ann R Coll Surg Engl</addtitle><date>2013-03</date><risdate>2013</risdate><volume>95</volume><issue>2</issue><spage>125</spage><epage>130</epage><pages>125-130</pages><issn>0035-8843</issn><eissn>1478-7083</eissn><abstract><![CDATA[An anaerobic threshold (AT) of <11 ml/min/kg can identify patients at high risk of cardiopulmonary complications after major surgery. The aim of this study was to assess the value of cardiopulmonary exercise testing (CPET) in predicting cardiopulmonary complications in high risk patients undergoing oesophagogastric cancer resection.
Between March 2008 and October 2010, 108 patients (83 men, 25 women) with a median age of 66 years (range: 38-84 years) underwent CPET before potentially curative resections for oesophagogastric cancers. Measured CPET variables included AT and maximum oxygen uptake at peak exercise (VO2 peak). Outcome measures were length of high dependency unit stay, length of hospital stay, unplanned intensive care unit (ICU) admission, and postoperative morbidity and mortality.
The mean AT and VO2 peak were 10.8 ml/min/kg (standard deviation [SD]: 2.8 ml/min/kg, range: 4.6-19.3 ml/min/kg) and 15.2 ml/min/kg (SD: 5.3 ml/min/kg, range: 5.4-33.3 ml/min/kg) respectively; 57 patients (55%) had an AT of <11 ml/min/kg and 26 (12%) had an AT of <9 ml/min/kg. Postoperative complications occurred in 57 patients (29 cardiopulmonary [28%] and 28 non-cardiopulmonary [27%]). Four patients (4%) died in hospital and 21 (20%) required an unplanned ICU admission. Cardiopulmonary complications occurred in 42% of patients with an AT of <9 ml/min/kg compared with 29% of patients with an AT of ≥9 ml/min/kg but <11 ml/min/kg and 20% of patients with an AT of ≥11 ml/min/kg (p = 0.04). There was a trend that those with an AT of <11 ml/min/kg and a low VO2 peak had a higher rate of unplanned ICU admission.
This study has shown a correlation between AT and the development of cardiopulmonary complications although the discriminatory ability was low.]]></abstract><cop>England</cop><pub>Royal College of Surgeons</pub><pmid>23484995</pmid><doi>10.1308/003588413X13511609954897</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Annals of the Royal College of Surgeons of England, 2013-03, Vol.95 (2), p.125-130 |
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| subjects | Adult Aged Aged, 80 and over Critical Care - statistics & numerical data Esophageal Neoplasms - surgery Exercise Test Heart Diseases - diagnosis Heart Diseases - etiology Humans Length of Stay - statistics & numerical data Lung Diseases - diagnosis Lung Diseases - etiology Middle Aged Oxygen Consumption - physiology Postoperative Complications - diagnosis Postoperative Complications - etiology Preoperative Care - methods ROC Curve Stomach Neoplasms - surgery Treatment Outcome Upper GI |
| title | Cardiopulmonary exercise testing as a predictor of complications in oesophagogastric cancer surgery |
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