Peripartum Cardiomyopathy: Current State of Knowledge, New Developments and Future Directions

Peripartum cardiomyopathy (PPCM) is a form of idiopathic dilated cardiomyopathy affecting women in late pregnancy or early puerperium. Although initially described in the late 1800s, it has only recently been recognized as a distinct cardiac condition. The reported incidence and prognosis varies acc...

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Bibliographic Details
Published in:Current cardiology reviews 2014-11, Vol.10 (4), p.317-326
Main Authors: Biteker, Murat, Kayatas, Kadir, Duman, Dursun, Turkmen, Muhsin, Bozkurt, Biykem
Format: Article
Language:English
Subjects:
Cardiomyopathy, Dilated - epidemiology
Cardiomyopathy, Dilated - physiopathology
Cardiomyopathy, Dilated - therapy
Disease Progression
Female
Heart Failure - etiology
Heart Failure - physiopathology
Heart Transplantation
Humans
Peripartum Period
Pregnancy
Pregnancy Complications, Cardiovascular - epidemiology
Pregnancy Complications, Cardiovascular - physiopathology
Pregnancy Complications, Cardiovascular - therapy
Prognosis
Puerperal Disorders - epidemiology
Puerperal Disorders - physiopathology
Puerperal Disorders - therapy
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Summary:Peripartum cardiomyopathy (PPCM) is a form of idiopathic dilated cardiomyopathy affecting women in late pregnancy or early puerperium. Although initially described in the late 1800s, it has only recently been recognized as a distinct cardiac condition. The reported incidence and prognosis varies according to geography. The clinical course varies between complete recovery to rapid progression to chronic heart failure, heart transplantation or death. In spite of significant improvements in understanding the pathophysiology and management of the PPCM many features of this unique disease are poorly understood, including incidence, etiology, epidemiology, pathophysiology, predictors of prognosis and optimal therapy. The present article revisits these concepts and recent advances in PPCM.
ISSN:1573-403X
1875-6557
1875-6557
DOI:10.2174/1573403X10666140320144048