The value of 18F-fluorodeoxyglucose positron emission tomography combined with computed tomography in the detection and characterization of soft tissue metastasis

Metastatic tumours presenting as soft tissue metastasis (STM) are relatively rare. STM represents metastasis to the muscle and subcutaneous tissues. The majority of the currently available clinical or radiological data on STM consist of isolated case reports or reviews. The aim of this study was to...

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Bibliographic Details
Published in:Molecular and clinical oncology 2014-09, Vol.2 (5), p.761-766
Main Authors: QIU, DA-SHENG, XU, LI-YING, SHAMES, SALMAN
Format: Article
Language:English
Subjects:
2D 18F-fluorodeoxyglucose positron emission tomography
computed tomography
Lung cancer
Lymphoma
Medical imaging
Melanoma
metastases
Metastasis
Oncology
Pathology
Patients
Skin cancer
soft tissue
Tomography
Tumors
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Summary:Metastatic tumours presenting as soft tissue metastasis (STM) are relatively rare. STM represents metastasis to the muscle and subcutaneous tissues. The majority of the currently available clinical or radiological data on STM consist of isolated case reports or reviews. The aim of this study was to report the manifestations, origin and distribution of STM detected by 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) and to assess the value of 18F-FDG PET/CT in the characterisation of STM. We reviewed 17 cases of patients with STM who underwent 18F-FDG PET/CT scanning. The imaging and clinical data of these patients were retrospectively analysed. This method is very sensitive in the detection of STM and provides ample information for clinical tumour staging. PET is more sensitive compared to CT in detecting lesions in muscle, before the density and morphology of the soft tissues are altered, providing a clear view within the soft tissue. Due to the limitations in resolution, PET is less sensitive compared to CT in detecting lesions in the subcutaneous tissues. The aim of this study was to improve our knowledge of 18F-FDG PET/CT findings in the diagnosis of STM and determine its value in the staging of malignant tumours.
ISSN:2049-9450
2049-9469
DOI:10.3892/mco.2014.312