Abnormal plasma clot structure and stability distinguish bleeding risk in patients with severe factor XI deficiency

Summary Background Factor XI (FXI) deficiency is a rare autosomal recessive disorder. Many patients with even very low FXI levels (

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Bibliographic Details
Published in:Journal of thrombosis and haemostasis 2014-07, Vol.12 (7), p.1121-1130
Main Authors: Zucker, M., Seligsohn, U., Salomon, O., Wolberg, A. S.
Format: Article
Language:English
Subjects:
Adult
Aged
bleeding
Blood Coagulation
Cohort Studies
factor XI
Factor XI - metabolism
factor XI deficiency
Factor XI Deficiency - blood
Factor XI Deficiency - diagnosis
Factor XIII - metabolism
Female
fibrin clot lysis time
Fibrinolysis
Hemorrhage - diagnosis
Humans
Male
Microscopy, Confocal
Middle Aged
Phospholipids - chemistry
Plasma - metabolism
plasma clot lysis time
Risk Factors
Thrombin - chemistry
von Willebrand Factor - metabolism
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Description
Summary:Summary Background Factor XI (FXI) deficiency is a rare autosomal recessive disorder. Many patients with even very low FXI levels (
ISSN:1538-7933
1538-7836
1538-7836
DOI:10.1111/jth.12600