Head fat is a novel method of measuring metabolic disorder in Chinese obese patients

Body adiposity, especially ectopic fat accumulation, has a range of metabolic and cardiovascular effects. The aim of this study was to investigate the association between head fat and metabolic values in Chinese obese patients. Data of this cross-sectional study from 66 obese patients were collected...

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Bibliographic Details
Published in:Lipids in health and disease 2014-07, Vol.13 (1), p.113-113, Article 113
Main Authors: Wang, Xing-chun, Liu, Huan, Huang, Yue-ye, Sun, Hang, Bu, Le, Qu, Shen
Format: Article
Language:English
Subjects:
Adiposity
Adult
Analysis
Area Under Curve
Blood Glucose
Body mass index
Cholesterol
Complications and side effects
Female
Head - pathology
Health aspects
Humans
Hyperlipidemias - blood
Hyperlipidemias - etiology
Hyperlipidemias - pathology
Hyperuricemia - blood
Hyperuricemia - etiology
Hyperuricemia - pathology
Insulin
Lipid Metabolism
Low density lipoprotein
Male
Measurement
Medical research
Medicine, Experimental
Metabolic disorders
Methods
Obesity
Obesity - blood
Obesity - complications
Obesity - pathology
Physiological aspects
ROC Curve
Subcutaneous Fat - pathology
Weight control
Young Adult
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Summary:Body adiposity, especially ectopic fat accumulation, has a range of metabolic and cardiovascular effects. The aim of this study was to investigate the association between head fat and metabolic values in Chinese obese patients. Data of this cross-sectional study from 66 obese patients were collected. Fat distribution was measured by dual-energy X-ray absorptiometry, and data of body weight, body mass index (BMI), neck circumference (NC), waist circumference (WC), hip circumference (HC), visceral index, basal metabolism (BM), glucose metabolism, lipid levels, uric acid (UA) had been collected. 1) Head fat was significantly associated with BMI, WC, HC, visceral index, BM, total fat and total fat excluding head fat in both males and females (p0.05). 2) Receiver operating characteristic analysis showed that a head fat of 1925.6 g and a head fat of 1567.85 g were the best cut-off values to determine subjects with low high-density lipoprotein cholesterol and hyperuricemia respectively. Head fat accumulation was closely associated with increased body fat, hyperinsulinemia, hyperuricemia, and impared lipid profile, suggesting it might be used as an indicator for dyslipidemia and hyperuricemia.
ISSN:1476-511X
1476-511X
DOI:10.1186/1476-511X-13-113